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BRENDA, AMENDA and FRENDA the enzyme information system: new content and tools in 2009
Open accessAbstract
The BRENDA (BRaunschweig ENzyme DAtabase) (http://www.brenda-enzymes.org) represents the largest freely available information system containing a huge amount of biochemical and molecular information on all classified enzymes as well as software tools for querying the database and calculating molecular properties. The database covers information on classification and nomenclature, reaction and specificity, functional parameters, occurrence, enzyme structure and stability, mutants and enzyme engineering, preparation and isolation, the application of enzymes, and ligand-related data. The data in BRENDA are manually curated from more than 79,000 primary literature references. Each entry is clearly linked to a literature reference, the origin organism and, where available, to the protein sequence of the enzyme protein. A new search option provides the access to protein-specific data. FRENDA (Full Reference ENzyme DAta) and AMENDA (Automatic Mining of ENzyme DAta) are additional databases created by continuously improved text-mining procedures. These databases ought to provide a complete survey on enzyme data of the literature collection of PubMed. The web service via a SOAP (Simple Object Access Protocol) interface for access to the BRENDA data has been further enhanced.
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BRENDA, the ELIXIR core data resource in 2021: new developments and updates
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“The closest has been the Brenda Tissue Ontology (BTO) [22], a terminology applicable across plants, fungi and animals, including gross anatomy, as well as cell types and diseases.”
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Metadata
- Authors
- Chang, A., Scheer, M., Grote, A., Schomburg, I., & Schomburg, D.
- Venue
- Nucleic Acids Research
- Publisher
- Oxford University Press (OUP)
- Published
- 2009-01-01
- Volume
- 37
- Issue
- Database
- Pages
- D588-D592
- ISSN
- 0305-1048 (ISSN-L)
- 1362-4962
- OpenAlex
- W2150700412
- Cited by
- 356
- References
- 0
- FWCI
- 22.58
- Type
- journal article
- Language
- en
- Open access
- gold
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- Chang, A., Scheer, M., Grote, A., Schomburg, I., & Schomburg, D. (2009). BRENDA, AMENDA and FRENDA the enzyme information system: new content and tools in 2009. Nucleic Acids Research. https://doi.org/10.1093/nar/gkn820
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