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Cited by 430

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The UniProt-GO Annotation database in 2011

Open access
Dimmer, E. C., Huntley, R. P., Alam-Faruque, Y., Sawford, T., O'Donovan, C., Martin, M. J., Bely, B., Browne, P., Mun Chan, W., Eberhardt, R., Gardner, M., Laiho, K., Legge, D., Magrane, M., Pichler, K., Poggioli, D., Sehra, H., Auchincloss, A., Axelsen, K., Blatter, M.-C., Boutet, E., Braconi-Quintaje, S., Breuza, L., Bridge, A., Coudert, E., Estreicher, A., Famiglietti, L., Ferro-Rojas, S., Feuermann, M., Gos, A., Gruaz-Gumowski, N., Hinz, U., Hulo, C., James, J., Jimenez, S., Jungo, F., Keller, G., Lemercier, P., Lieberherr, D., Masson, P., Moinat, M., Pedruzzi, I., Poux, S., Rivoire, C., Roechert, B., Schneider, M., Stutz, A., Sundaram, S., Tognolli, M., Bougueleret, L., Argoud-Puy, G., Cusin, I., Duek- Roggli, P., Xenarios, I., Apweiler, R.·2012·Nucleic Acids Research

Abstract

The GO annotation dataset provided by the UniProt Consortium (GOA: http://www.ebi.ac.uk/GOA) is a comprehensive set of evidenced-based associations between terms from the Gene Ontology resource and UniProtKB proteins. Currently supplying over 100 million annotations to 11 million proteins in more than 360,000 taxa, this resource has increased 2-fold over the last 2 years and has benefited from a wealth of checks to improve annotation correctness and consistency as well as now supplying a greater information content enabled by GO Consortium annotation format developments. Detailed, manual GO annotations obtained from the curation of peer-reviewed papers are directly contributed by all UniProt curators and supplemented with manual and electronic annotations from 36 model organism and domain-focused scientific resources. The inclusion of high-quality, automatic annotation predictions ensures the UniProt GO annotation dataset supplies functional information to a wide range of proteins, including those from poorly characterized, non-model organism species. UniProt GO annotations are freely available in a range of formats accessible by both file downloads and web-based views. In addition, the introduction of a new, normalized file format in 2010 has made for easier handling of the complete UniProt-GOA data set.

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Metadata

Authors
Dimmer, E. C., Huntley, R. P., Alam-Faruque, Y., Sawford, T., O'Donovan, C., Martin, M. J., Bely, B., Browne, P., Mun Chan, W., Eberhardt, R., Gardner, M., Laiho, K., Legge, D., Magrane, M., Pichler, K., Poggioli, D., Sehra, H., Auchincloss, A., Axelsen, K., Blatter, M.-C., Boutet, E., Braconi-Quintaje, S., Breuza, L., Bridge, A., Coudert, E., Estreicher, A., Famiglietti, L., Ferro-Rojas, S., Feuermann, M., Gos, A., Gruaz-Gumowski, N., Hinz, U., Hulo, C., James, J., Jimenez, S., Jungo, F., Keller, G., Lemercier, P., Lieberherr, D., Masson, P., Moinat, M., Pedruzzi, I., Poux, S., Rivoire, C., Roechert, B., Schneider, M., Stutz, A., Sundaram, S., Tognolli, M., Bougueleret, L., Argoud-Puy, G., Cusin, I., Duek- Roggli, P., Xenarios, I., & Apweiler, R.
Venue
Nucleic Acids Research
Published
2011-11-28
Volume
40
Issue
D1
Pages
D565-D570
ISSN
  • 0305-1048 (ISSN-L)
  • 1362-4962
OpenAlex
W2163603537
Cited by
430
References
2
FWCI
14.58
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: The UniProt-GO Annotation database in 2011. https://app.cochat.ai/papers/10.1093/nar/gkr1048
The paper
Dimmer, E. C., Huntley, R. P., Alam-Faruque, Y., Sawford, T., O'Donovan, C., Martin, M. J., Bely, B., Browne, P., Mun Chan, W., Eberhardt, R., Gardner, M., Laiho, K., Legge, D., Magrane, M., Pichler, K., Poggioli, D., Sehra, H., Auchincloss, A., Axelsen, K., . . . Apweiler, R. (2012). The UniProt-GO Annotation database in 2011. Nucleic Acids Research. https://doi.org/10.1093/nar/gkr1048

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