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BioProject and BioSample databases at NCBI: facilitating capture and organization of metadata

Open access
Barrett, T., Clark, K., Gevorgyan, R., Gorelenkov, V., Gribov, E., Karsch-Mizrachi, I., Kimelman, M., Pruitt, K. D., Resenchuk, S., Tatusova, T., Yaschenko, E., Ostell, J.·2012·Nucleic Acids Research

Abstract

As the volume and complexity of data sets archived at NCBI grow rapidly, so does the need to gather and organize the associated metadata. Although metadata has been collected for some archival databases, previously, there was no centralized approach at NCBI for collecting this information and using it across databases. The BioProject database was recently established to facilitate organization and classification of project data submitted to NCBI, EBI and DDBJ databases. It captures descriptive information about research projects that result in high volume submissions to archival databases, ties together related data across multiple archives and serves as a central portal by which to inform users of data availability. Concomitantly, the BioSample database is being developed to capture descriptive information about the biological samples investigated in projects. BioProject and BioSample records link to corresponding data stored in archival repositories. Submissions are supported by a web-based Submission Portal that guides users through a series of forms for input of rich metadata describing their projects and samples. Together, these databases offer improved ways for users to query, locate, integrate and interpret the masses of data held in NCBI's archival repositories. The BioProject and BioSample databases are available at http://www.ncbi.nlm.nih.gov/bioproject and http://www.ncbi.nlm.nih.gov/biosample, respectively.

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Metadata

Authors
Barrett, T., Clark, K., Gevorgyan, R., Gorelenkov, V., Gribov, E., Karsch-Mizrachi, I., Kimelman, M., Pruitt, K. D., Resenchuk, S., Tatusova, T., Yaschenko, E., & Ostell, J.
Venue
Nucleic Acids Research
Published
2011-12-01
Volume
40
Issue
D1
Pages
D57-D63
ISSN
  • 0305-1048 (ISSN-L)
  • 1362-4962
OpenAlex
W2036288429
Cited by
347
References
0
FWCI
48.09
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: BioProject and BioSample databases at NCBI: facilitating capture and organization of metadata. https://app.cochat.ai/papers/10.1093/nar/gkr1163
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Barrett, T., Clark, K., Gevorgyan, R., Gorelenkov, V., Gribov, E., Karsch-Mizrachi, I., Kimelman, M., Pruitt, K. D., Resenchuk, S., Tatusova, T., Yaschenko, E., & Ostell, J. (2012). BioProject and BioSample databases at NCBI: facilitating capture and organization of metadata. Nucleic Acids Research. https://doi.org/10.1093/nar/gkr1163

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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