Assembly: a resource for assembled genomes at NCBI
Open accessAbstract
The NCBI Assembly database (www.ncbi.nlm.nih.gov/assembly/) provides stable accessioning and data tracking for genome assembly data. The model underlying the database can accommodate a range of assembly structures, including sets of unordered contig or scaffold sequences, bacterial genomes consisting of a single complete chromosome, or complex structures such as a human genome with modeled allelic variation. The database provides an assembly accession and version to unambiguously identify the set of sequences that make up a particular version of an assembly, and tracks changes to updated genome assemblies. The Assembly database reports metadata such as assembly names, simple statistical reports of the assembly (number of contigs and scaffolds, contiguity metrics such as contig N50, total sequence length and total gap length) as well as the assembly update history. The Assembly database also tracks the relationship between an assembly submitted to the International Nucleotide Sequence Database Consortium (INSDC) and the assembly represented in the NCBI RefSeq project. Users can find assemblies of interest by querying the Assembly Resource directly or by browsing available assemblies for a particular organism. Links in the Assembly Resource allow users to easily download sequence and annotations for current versions of genome assemblies from the NCBI genomes FTP site.
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The number of vertebrate genome assemblies in the NCBI database increased by more than 50% to 1,485 assemblies in the year from July 2018 to July 2019.
“the number of vertebrate genome assemblies currently in the NCBI (National Center for Biotechnology Information) database4 increased by more than 50% to 1,485 assemblies in the year from July 2018 to July 2019.”
From Progressive Cactus is a multiple-genome aligner for the thousand-genome era (2020) · cites this paper as [4]
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- Authors
- Kitts, P. A., Church, D. M., Thibaud-Nissen, F., Choi, J., Hem, V., Sapojnikov, V., Smith, R. G., Tatusova, T., Xiang, C., Zherikov, A., DiCuccio, M., Murphy, T. D., Pruitt, K. D., & Kimchi, A.
- Affiliations
- National Institutes of Health (US)
- Corresponding author
- Kitts, Paul A.
- ORCID
- Venue
- Nucleic Acids Research
- Publisher
- Oxford University Press (OUP)
- Published
- 2015-11-17
- Volume
- 44
- Issue
- D1
- Pages
- D73-D80
- ISSN
- 0305-1048 (ISSN-L)
- 1362-4962
- PMC
- PMC4702866
- OpenAlex
- W2225557190
- Cited by
- 398
- References
- 3
- Citations by year
- 2026: 42 · 2025: 53 · 2024: 68 · 2023: 45 · 2022: 45 · 2021: 52 · 2020: 34 · 2019: 18 · 2018: 18 · 2017: 10 · 2016: 10 · 2015: 2
- FWCI
- 5.26
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- public-domain
- Locations
- Nucleic Acids Research (publishedVersion, public-domain)
- Europe PMC (PubMed Central) (publishedVersion, public-domain)
- PubMed Central (publishedVersion, public-domain)
- PubMed (publishedVersion)
- HighWire Press Open Archive (submittedVersion)
- Funders
- National Institutes of Health
- National Cancer Institute (R01CA094025)
- U.S. National Library of Medicine
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Phylogenetic Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genetics, Bioinformatics, and Biomedical Research
- Physical Sciences › Computer Science › Information Systems › Research Data Management Practices
- Keywords
- genome assembly, NCBI RefSeq
- MeSH terms
- Animals, Humans, Genome, Internet, Genomics, Databases, Nucleic Acid, Mice
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