Cited by 158Genetic diversity and population structureGenomics and Phylogenetic StudiesVeterinary Oncology Research

The Value of Reference Genomes in the Conservation of Threatened Species

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Brandies, Parice, Peel, Emma, Hogg, Carolyn J., Belov, Katherine·2019·Genes

Abstract

Conservation initiatives are now more crucial than ever—over a million plant and animal species are at risk of extinction over the coming decades. The genetic management of threatened species held in insurance programs is recommended; however, few are taking advantage of the full range of genomic technologies available today. Less than 1% of the 13505 species currently listed as threated by the International Union for Conservation of Nature (IUCN) have a published genome. While there has been much discussion in the literature about the importance of genomics for conservation, there are limited examples of how having a reference genome has changed conservation management practice. The Tasmanian devil (Sarcophilus harrisii), is an endangered Australian marsupial, threatened by an infectious clonal cancer devil facial tumor disease (DFTD). Populations have declined by 80% since the disease was first recorded in 1996. A reference genome for this species was published in 2012 and has been crucial for understanding DFTD and the management of the species in the wild. Here we use the Tasmanian devil as an example of how a reference genome has influenced management actions in the conservation of a species.

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Research works printed but not linked: 3

  1. [56]Grueber C.E. Chong R. Gooley R.M. McLennan E.A. Barrs V.R. Belov K. Hogg C.J. Genetic analysis of scat samples to inform conservation of Tasmanian devil Aust. Zool. (In press)
  2. [63]Hogg C.J. McLennan E.A. Wise P. Lee A. Pemberton D. Fox S. Belov K. Grueber C.E. Preserving the integrity of a single source population during multiple translocations Biol. Conserv. (In press)
  3. [68]McLennan E.A. Grueber C.E. Wise P. Belov K. Hogg C.J. Mixing genetic lineages sucessfully boosts diversity of an endangered carnivore Anim. Conserv. (under review)

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Authors
Brandies, P., Peel, E., Hogg, C. J., & Belov, K.
Affiliations
The University of Sydney (AU)
Corresponding author
Belov, Katherine
Venue
Genes
Publisher
MDPI AG
Published
2019-10-25
Volume
10
Issue
11
Pages
846
ISSN
2073-4425 (ISSN-L)
OpenAlex
W2981549736
Cited by
158
References
113
Citations by year
2026: 16 · 2025: 29 · 2024: 25 · 2023: 28 · 2022: 24 · 2021: 22 · 2020: 11 · 2019: 1 · 2018: 1
FWCI
1.95
Type
journal article
Language
en
Open access
Locations
  • Genes (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
Australian Research Council (LP140100508, DP180102465)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic diversity and population structure
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Phylogenetic Studies
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Veterinary Oncology Research
Keywords
reference genome, conservation genomics, threatened species, Tasmanian devil, devil facial tumour disease, insurance population, genetic management, extinction risk, marsupials
MeSH terms
Animals, Marsupialia, Reference Standards, Genome, Genomics, Endangered Species, Genotyping Techniques

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