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tRNAscan-SE On-line: integrating search and context for analysis of transfer RNA genes

Open access
Lowe, Todd M., Chan, Patricia P.·2016·Nucleic Acids Research

Abstract

High-throughput genome sequencing continues to grow the need for rapid, accurate genome annotation and tRNA genes constitute the largest family of essential, ever-present non-coding RNA genes. Newly developed tRNAscan-SE 2.0 has advanced the state-of-the-art methodology in tRNA gene detection and functional prediction, captured by rich new content of the companion Genomic tRNA Database. Previously, web-server tRNA detection was isolated from knowledge of existing tRNAs and their annotation. In this update of the tRNAscan-SE On-line resource, we tie together improvements in tRNA classification with greatly enhanced biological context via dynamically generated links between web server search results, the most relevant genes in the GtRNAdb and interactive, rich genome context provided by UCSC genome browsers. The tRNAscan-SE On-line web server can be accessed at http://trna.ucsc.edu/tRNAscan-SE/.

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Metadata

Authors
Lowe, T. M., & Chan, P. P.
Venue
Nucleic Acids Research
Published
2016-05-12
Volume
44
Issue
W1
Pages
W54-W57
ISSN
  • 0305-1048 (ISSN-L)
  • 1362-4962
OpenAlex
W2393535458
Cited by
2,709
References
1
FWCI
84.27
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: tRNAscan-SE On-line: integrating search and context for analysis of transfer RNA genes. https://app.cochat.ai/papers/10.1093/nar/gkw413
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Lowe, T. M., & Chan, P. P. (2016). tRNAscan-SE On-line: integrating search and context for analysis of transfer RNA genes. Nucleic Acids Research. https://doi.org/10.1093/nar/gkw413

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