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ARED-Plus: an updated and expanded database of AU-rich element-containing mRNAs and pre-mRNAs
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AREs play a crucial role in regulating mRNA stability and are present in 22% of all human 3′UTRs, establishing them as the most common regulatory motifs for mRNA stability.
“These AREs play a crucial role in regulating mRNA stability and are present in 22 % of all human 3′UTRs, establishing them as the most common regulatory motifs for mRNA stability [26].”
From The low-density lipoprotein receptor: Emerging post-transcriptional regulatory mechanisms (2025) · cites this paper as [26]
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Research works printed but not linked: 14
- 2004, The involvement of AU-rich element-binding proteins in p38 mitogen-activated protein kinase pathway-mediated mRNA stabilisation, Cell. Signal., 16, 1113, 10.1016/j.cellsig.2004.04.006 · DOI
- 2011, Turnover of AU-rich-containing mRNAs during stress: a matter of survival, Wiley interdiscipl. Rev. RNA, 2, 336, 10.1002/wrna.55 · DOI
- 2014, Translational regulation of specific mRNAs controls feedback inhibition and survival during macrophage activation, PLoS Genet., 10, e1004368, 10.1371/journal.pgen.1004368 · DOI
- 2001, ARED: human AU-rich element-containing mRNA database reveals an unexpectedly diverse functional repertoire of encoded proteins, Nucleic Acids Res., 29, 246, 10.1093/nar/29.1.246 · DOI
- 2008, ARED Organism: expansion of ARED reveals AU-rich element cluster variations between human and mouse, Nucleic Acids Res., 36, D137
- 2011, Transcriptome-wide analysis of regulatory interactions of the RNA-binding protein HuR, Mol. Cell, 43, 340, 10.1016/j.molcel.2011.06.008 · DOI · Paper page
- 2011, Integrative regulatory mapping indicates that the RNA-binding protein HuR couples pre-mRNA processing and mRNA stability, Mol. Cell, 43, 327, 10.1016/j.molcel.2011.06.007 · DOI · Paper page
- 2016, Tristetraprolin binding site atlas in the macrophage transcriptome reveals a switch for inflammation resolution, Mol. Syst. Biol., 12, 868, 10.15252/msb.20156628 · DOI
- 2014, PAR-CLIP analysis uncovers AUF1 impact on target RNA fate and genome integrity, Nat. Commun., 5, 5248, 10.1038/ncomms6248 · DOI · Paper page
- 2017, Maintenance of the marginal-zone B cell compartment specifically requires the RNA-binding protein ZFP36L1, Nat. Immunol., 18, 683, 10.1038/ni.3724 · DOI
- 2014, Global target mRNA specification and regulation by the RNA-binding protein ZFP36, Genome Biol., 15, R12, 10.1186/gb-2014-15-1-r12 · DOI
- 2016, AREsite2: an enhanced database for the comprehensive investigation of AU/GU/U-rich elements, Nucleic Acids Res., 44, D90, 10.1093/nar/gkv1238 · DOI
- 2012, Genome-wide assessment of AU-rich elements by the AREScore algorithm, PLoS Genet., 8, e1002433, 10.1371/journal.pgen.1002433 · DOI
- 2017, Hallmarks of cancer and AU-rich elements, Wiley Interdiscipl. Rev. RNA, 8
Cited by
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Nicolet, B. P., & Wolkers, M. C. (2022) · PLOS ONE · doi:10.1371/journal.pone.0276294 · Cited by 62
The low-density lipoprotein receptor: Emerging post-transcriptional regulatory mechanisms
Ndoj, K., Meurs, A., Papaioannou, D., Bjune, K., & Zelcer, N. (2025) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2024.119082 · Cited by 17
Metadata
- Authors
- Bakheet, T., Hitti, E., & Khabar, K. S. A.
- ORCID
- Khabar, Khalid S A
- Venue
- Nucleic Acids Research
- Publisher
- Oxford University Press (OUP)
- Published
- 2017-10-25
- Volume
- 46
- Issue
- D1
- Pages
- D218-D220
- ISSN
- 0305-1048
- 1362-4962
- PMC
- PMC5753209
- Cited by
- 92
- References
- 0
- Language
- en
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