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PAR-CLIP analysis uncovers AUF1 impact on target RNA fate and genome integrity

Yoon, Je-Hyun, De, Supriyo, Srikantan, Subramanya, Abdelmohsen, Kotb, Grammatikakis, Ioannis, Kim, Jiyoung, Kim, Kyoung Mi, Noh, Ji Heon, White, Elizabeth J. F., Martindale, Jennifer L., Yang, Xiaoling, Kang, Min-Ju, Wood, William H., Hooten, Nicole Noren, Evans, Michele K., Becker, Kevin G., Tripathi, Vidisha, Prasanth, Kannanganattu V., Wilson, Gerald M., Tuschl, Thomas, Ingolia, Nicholas T., Hafner, Markus, Gorospe, Myriam·2014·Nature Communications
DOI 10.1038/ncomms6248PMC PMC4291169
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  • In the cytoplasm, AUF1 binds U-, GU- and UG-rich sequences and either promotes decay or enhances stability and translation of target mRNAs by poorly understood mechanisms.

    “In the cytoplasm, it binds U-, GU- and UG-rich sequences and either promotes decay or enhances the stability and translation of target mRNAs by mechanisms that are still poorly understood [14].”

    From RNA binding protein AUF1/HNRNPD regulates nuclear export, stability and translation of SNCA transcripts (2023) · cites this paper as [14]

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Research works printed but not linked: 50

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Metadata

Authors
Yoon, J.-H., De, S., Srikantan, S., Abdelmohsen, K., Grammatikakis, I., Kim, J., Kim, K. M., Noh, J. H., White, E. J. F., Martindale, J. L., Yang, X., Kang, M.-J., Wood, W. H., Hooten, N. N., Evans, M. K., Becker, K. G., Tripathi, V., Prasanth, K. V., Wilson, G. M., Tuschl, T., Ingolia, N. T., Hafner, M., & Gorospe, M.
Venue
Nature Communications
Publisher
Springer Science and Business Media LLC
Published
2014-11-04
Volume
5
Issue
1
ISSN
2041-1723
DOI
10.1038/ncomms6248
PMC
PMC4291169
Cited by
174
References
4
Language
en
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