The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Fast chromatin immunoprecipitation assay
Open accessAbstract
Chromatin immunoprecipitation (ChIP) is a widely used method to explore in vivo interactions between proteins and DNA. The ChIP assay takes several days to complete, involves several tube transfers and uses either phenol-chlorophorm or spin columns to purify DNA. The traditional ChIP method becomes a challenge when handling multiple samples. We have developed an efficient and rapid Chelex resin-based ChIP procedure that dramatically reduces time of the assay and uses only a single tube to isolate PCR-ready DNA. This method greatly facilitates the probing of chromatin changes over many time points with several antibodies in one experiment.
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Cites
Transcriptional activation by recruitment
Ptashne, M., & Gann, A. (1997) · Nature · doi:10.1038/386569a0 · Cited by 1,158 · cited 1×
“The recruitment of RNA polymerase II is a highly regulated key step controlling the rate of mRNA synthesis from target gene loci (4,29).”
BackgroundEvidence for nucleosome depletion at active regulatory regions genome-wide
Lee, C.-K., Shibata, Y., Rao, B., Strahl, B. D., & Lieb, J. D. (2004) · Nature Genetics · doi:10.1038/ng1400 · Cited by 738
Cited by
High-throughput genotyping by whole-genome resequencing
Huang, X., Feng, Q., Qian, Q., Zhao, Q., Wang, L., Wang, A., Guan, J., Fan, D., Weng, Q., Huang, T., et al. (2009) · Genome Research · doi:10.1101/gr.089516.108 · Cited by 910
Protocol for the fast chromatin immunoprecipitation (ChIP) method
Nelson, J. D., Denisenko, O., & Bomsztyk, K. (2006) · Nature Protocols · doi:10.1038/nprot.2006.27 · Cited by 770
Self-citationYu, X., Li, L., Zola, J., Aluru, M., Ye, H., Foudree, A., Guo, H., Anderson, S., Aluru, S., Liu, P., et al. (2011) · The Plant Journal · doi:10.1111/j.1365-313x.2010.04449.x · Cited by 666
Qiu, J., Fiil, B. K., Petersen, K., Nielsen, H. B., Botanga, C. J., Thorgrimsen, S., Palma, K., Suarez‐Rodriguez, M. C., Sandbech‐Clausen, S., Lichota, J., et al. (2008) · The EMBO Journal · doi:10.1038/emboj.2008.147 · Cited by 503
Wang, T., Chen, K., Zeng, X., Yang, J., Wu, Y., Shi, X., Qin, B., Zeng, L., Esteban, M. A., Pan, G., et al. (2011) · Cell Stem Cell · doi:10.1016/j.stem.2011.10.005 · Cited by 458
Metadata
- Authors
- Nelson, J. D.
- Venue
- Nucleic Acids Research
- Publisher
- Oxford University Press (OUP)
- Published
- 2006-01-08
- Volume
- 34
- Issue
- 1
- Pages
- e2-e2
- ISSN
- 0305-1048 (ISSN-L)
- 1362-4962
- OpenAlex
- W1984632551
- Cited by
- 235
- References
- 2
- FWCI
- 8.72
- Type
- journal article
- Language
- en
- Open access
- gold
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