Cited by 229Cardiovascular Function and Risk FactorsDialysis and Renal Disease ManagementChronic Kidney Disease and Diabetes

Left ventricular alterations and end‐stage renal disease

London, Gerard M.·2002·Nephrology Dialysis Transplantation

Abstract

The prevalence of left ventricular (LV) changes, especially LV hypertrophy (LVH), is high among patients with chronic kidney disease and end-stage renal disease (ESRD). Ventricular enlargement usually is associated with normal systolic function and increased stroke and cardiac index. In the absence of intrinsic heart disease, LV enlargement is most probably attributable to chronic volume/flow overload associated with anaemia, the presence of arteriovenous shunts, and sodium and water retention. In ESRD patients, hypertension is also a leading cause of LVH, but structural LV changes and myocardial fibrosis may also be due to non-haemodynamic factors such as angiotensin II, parathyroid hormone, endothelin, aldosterone, increased sympathetic nerve discharge and increased plasma catecholamines. To improve the clinical outcomes in ESRD, it is essential to prevent LVH and its complications by correcting the factors that contribute to flow and pressure overload, including anaemia.

Integrity signals

Registry

Crossref · 10.1093/ndt/17.suppl_1.29

Cites

48 of 48 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Under chronic anemic conditions, adjustments that initially increase cardiac output lead to left ventricular enlargement and eccentric left ventricular hypertrophy.

    “Under chronic anemic conditions, adjustments that initially increase cardiac output lead to left ventricular enlargement and eccentric left ventricular hypertrophy (112).”

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
London, G. M.
Affiliations
Centre Hospitalier Frèderic-Henri Manhès (FR)
Corresponding author
London, Gerard M.
Venue
Nephrology Dialysis Transplantation
Published
2002-01-01
Volume
17
Issue
suppl_1
Pages
29-36
ISSN
  • 0931-0509 (ISSN-L)
  • 1460-2385
OpenAlex
W2109011321
Cited by
229
References
48
Citations by year
2026: 7 · 2025: 7 · 2024: 4 · 2023: 12 · 2022: 11 · 2021: 12 · 2020: 9 · 2019: 5 · 2018: 10 · 2017: 10 · 2016: 11 · 2015: 12 · 2014: 5 · 2013: 14 · 2012: 15
FWCI
5.92
Type
journal article
Language
en
Open access
closed
Locations
  • Nephrology Dialysis Transplantation (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
  • Health Sciences › Medicine › Nephrology › Dialysis and Renal Disease Management
  • Health Sciences › Medicine › Nephrology › Chronic Kidney Disease and Diabetes
Keywords
left ventricular hypertrophy, end-stage renal disease, chronic kidney disease, left ventricular dilatation, fluid overload, anemia, arteriovenous shunt, sodium and water retention, hypertension, myocardial fibrosis, angiotensin II, parathyroid hormone, endothelin, aldosterone, sympathetic nervous system, catecholamines, left ventricular function
MeSH terms
Hemodynamics, Humans, Hypertension, Kidney Failure, Chronic, Hypertrophy, Left Ventricular

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review