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Bladder Cancer
Abstract
In the United States, an estimated 74,000 new cases of bladder cancer and 16,000 deaths occur annually. Because of favorable survival, approximately 578,000 persons are alive after diagnosis. Recurrence after treatment is common, necessitating lifelong surveillance and care, making bladder cancer the most costly malignancy from diagnosis to death. The median age at diagnosis has increased from 67 years in 1980 to 73 years in 2008–2012. Incidence rates rise dramatically with age, suggesting that as the US population ages, the burden of bladder cancer in the United States will continue to grow. Worldwide over 1.3 million cases are estimated to occur annually. Cigarette smoking is the principal known cause of bladder cancer, along with various chemical exposures. Recent studies suggest that, over the past two decades, the risk for current smokers has increased from three times the risk of nonsmokers to about four to five times the nonsmoker risk.
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The epidemiology of bladder cancer varies by region, with tobacco smoking, occupational exposures (e.g., aromatic amines), and arsenic contamination of drinking water among the putative causes in industrialized countries.
“The epidemiology of bladder cancer varies by region, with tobacco smoking, occupational exposures (e.g., aromatic amines), and arsenic contamination of drinking water among the putative causes in industrialized countries.159,160”
From Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. (2024) · cites this paper as [159]
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Self-citation
Metadata
- Authors
- Silverman, D. T., Koutros, S., Figueroa, J. D., Prokunina-Olsson, L., & Rothman, N.
- Venue
- Oxford Scholarship Online
- Publisher
- Oxford University Press
- Published
- 2017-12-21
- OpenAlex
- W4248055173
- Cited by
- 16
- References
- 0
- Citations by year
- 2026: 5 · 2025: 2 · 2024: 3 · 2023: 4 · 2022: 2
- FWCI
- 0.00
- Type
- book
- Language
- en
- Open access
- closed
- Locations
- Oxford University Press eBooks (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Bladder and Urothelial Cancer Treatments
- Health Sciences › Medicine › Surgery › Urinary and Genital Oncology Studies
- Health Sciences › Medicine › Urology › Urinary Bladder and Prostate Research
- Keywords
- bladder cancer, incidence, mortality, survival, recurrence, surveillance (medicine), cancer treatment costs, population aging, cigarette smoking, chemical exposure, risk factors, global burden
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