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Investigations
Abstract
It may be that I have stumbled upon an adequate description of life itself. These modest yet profound words trumpet an imminent paradigm shift in scientific, economic, and technological thinking. In the tradition of Schrödinger’s classic What Is Life?, Kauffman’s Investigations is a tour-de-force exploration of the very essence of life itself, with conclusions that radically undermine the scientific approaches on which modern science rests--the approaches of Newton, Boltzman, Bohr, and Einstein. Building on his pivotal ideas about order and evolution in complex life systems, Kauffman finds that classical science does not take into account that physical systems--such as people in a biosphere--effect their dynamic environments in addition to being affected by them. These systems act on their own behalf as autonomous agents, but what defines them as such? In other words, what is life? Kauffman supplies a novel answer that goes beyond traditional scientific thinking by defining and explaining autonomous agents and work in the contexts of thermodynamics and of information theory. Much of Investigations unpacks the progressively surprising implications of his definition. Significantly, he sets the stages for a technological revolution in the coming decades. Scientists and engineers may soon seek to create autonomous agents--both organic and mechanical--that can not only construct things and work, but also reproduce themselves! Kauffman also lays out a foundation for a new concept of organization, and explores the requirements for the emergence of a general biology that will transcend terrestrial biology to seek laws governing biospheres anywhere in the cosmos. Moreover, he presents four candidate laws to explain how autonomous agents co-create their biosphere and the startling idea of a “co-creating” cosmos. A showcase of Kauffman’s most fundamental and significant ideas, Investigations presents a new way of thinking about the fundamentals of general biology that will change the way we understand life itself--on this planet and anywhere else in the cosmos.
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“This corresponds to the critical regime of RBNs, which has been associated with complexity and the possibility of life (Kauffman, 2000).”
From Information Measures of Complexity, Emergence, Self-organization, Homeostasis, and Autopoiesis (2013) · cites this paper as Kauffman, 2000
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Defining Agency: Individuality, Normativity, Asymmetry, and Spatio-temporality in Action
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Heart-Rate Variability—More than Heart Beats?
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A Universal Definition of Life: Autonomy and Open-Ended Evolution
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Self-citationTowards an evolutionary theory of the origin of life based on kinetics and thermodynamics
Pascal, R., Pross, A., & Sutherland, J. D. (2013) · Open Biology · doi:10.1098/rsob.130156 · Cited by 228
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Jen, E. (2003) · Complexity · doi:10.1002/cplx.10077 · Cited by 183
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Solée, R. V., Valverde, S., Casals, M. R., Kauffman, S. A., Farmer, D., & Eldredge, N. (2013) · Complexity · doi:10.1002/cplx.21436 · Cited by 140
Self-citationCausation and the Origin of Life. Metabolism or Replication First?
Pross, A. (2004) · Origins of life and evolution of the biosphere · doi:10.1023/b:orig.0000016446.51012.bc · Cited by 122
The Role of Atmospheric Aerosols in the Origin Of Life
Tuck, A. (2002) · Surveys in Geophysics · doi:10.1023/a:1020123922767 · Cited by 99
Enabling conditions for ‘open-ended evolution’
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Approaches to the Origin of Life on Earth
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Self-citationThe protometabolic nature of prebiotic chemistry
Nogal, N., Sanz-Sánchez, M., Vela-Gallego, S., Ruiz-Mirazo, K., & de la Escosura, A. (2023) · Chemical Society Reviews · doi:10.1039/d3cs00594a · Cited by 61
Hidden Concepts in the History and Philosophy of Origins-of-Life Studies: A Workshop Report
Mariscal, C., Barahona, A., Aubert-Kato, N., Aydinoglu, A. U., Bartlett, S., Cárdenas, M. L., Chandru, K., Cleland, C., Cocanougher, B. T., Comfort, N., et al. (2019) · Origins of Life and Evolution of Biospheres · doi:10.1007/s11084-019-09580-x · Cited by 36
Fundamental constraints to the logic of living systems
Solé, R., Kempes, C. P., Corominas-Murtra, B., De Domenico, M., Kolchinsky, A., Lachmann, M., Libby, E., Saavedra, S., Smith, E., & Wolpert, D. (2024) · Interface Focus · doi:10.1098/rsfs.2024.0010 · Cited by 34
Chiral Symmetry Breaking Phenomenon Caused by a Phase Transition
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Human innovation and the creative agency of the world in the age of generative AI
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The loneliness of the enactive cell: Towards a bio-enactive framework
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Björneborn, L. (2020) · The Palgrave Encyclopedia of the Possible · doi:10.1007/978-3-319-98390-5_100-1 · Cited by 18
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Self-citationOn the positive role of noise and error in complex systems
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Minimal model explanations of cognition
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Information Measures of Complexity, Emergence, Self-organization, Homeostasis, and Autopoiesis
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Metadata
- Authors
- Kauffman, S. A.
- Corresponding author
- Kauffman, Stuart A
- ORCID
- Kauffman, Stuart A
- Publisher
- Oxford University PressNew York, NY
- Published
- 2000-10-26
- OpenAlex
- W4388299828
- Cited by
- 950
- References
- 0
- Citations by year
- 2026: 67 · 2025: 65 · 2024: 53 · 2023: 50 · 2022: 33 · 2021: 45 · 2020: 54 · 2019: 44 · 2018: 29 · 2017: 24 · 2016: 27 · 2015: 29 · 2014: 27 · 2013: 46 · 2012: 39
- FWCI
- 12.35
- Type
- book
- Language
- en
- Open access
- closed
- Topics
- Physical Sciences › Physics and Astronomy › Statistical and Nonlinear Physics › Complex Systems and Dynamics
- Social Sciences › Arts and Humanities › History and Philosophy of Science › Philosophy of Biology and Scientific Explanation
- Physical Sciences › Physics and Astronomy › Astronomy and Astrophysics › Origins and Evolution of Life
- Keywords
- nature of life, autonomous agents, self-replication, thermodynamics, information theory, general biology, emergence, biosphere, self-organization, cosmology, Stuart Kauffman
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