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PHYSICAL ACTIVITY AS AN INDEX OF HEART ATTACK RISK IN COLLEGE ALUMNI1
Abstract
Risk of first heart attack was found to be related inversely to energy expenditure reported by 16,936 Harvard male alumni, aged 35-74 years, of whom 572 experienced heart attacks in 117,680 person-years of followup. Stairs climbed, blocks walked, strenuous sports played, and a composite physical activity index all opposed risk. Men with index below 2000 kilocalories per week were at 64% higher risk than classmates with higher index. Adult exercise was independent of other influences on heart attack risk, and peak exertion as strenuous sports play enhanced the effect of total energy expenditure. Notably, alumni physical activity supplanted student athleticism assessed in college 16-50 years earlier. If it is postulated that varsity athlete status implies selective cardiovascular fitness, such selection alone is insufficient to explain lower heart attack risk in later adult years. Ex-varsity athletes retained lower risk only if they maintained a high physical activity index as alumni.
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“People who exercise regularly not only have a lower base-line risk of myocardial infarction, but as demonstrated by this study, they also have a lower relative risk that an infarction will be triggered by heavy physical exertion.”
From Triggering of Acute Myocardial Infarction by Heavy Physical Exertion -- Protection against Triggering by Regular Exertion (1993) · cites this paper as [28]
In the citing paper
“numerous studies5,24-31 have found that regular exercise is associated with a reduction in the long-term risk of coronary events.”
From Triggering of Acute Myocardial Infarction by Heavy Physical Exertion -- Protection against Triggering by Regular Exertion (1993) · cites this paper as [28]
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Metadata
- Authors
- PAFFENBARGER, R. S., WING, A. L., & HYDE, R. T.
- Affiliations
- Harvard University (US)
- Corresponding author
- PAFFENBARGER, RALPH S.
- Venue
- American Journal of Epidemiology
- Publisher
- Oxford University Press (OUP)
- Published
- 1978-09
- Volume
- 108
- Issue
- 3
- Pages
- 161-175
- ISSN
- 0002-9262 (ISSN-L)
- 1476-6256
- OpenAlex
- W2147078612
- Cited by
- 1,980
- References
- 0
- Citations by year
- 2026: 10 · 2025: 22 · 2024: 30 · 2023: 23 · 2022: 24 · 2021: 36 · 2020: 40 · 2019: 40 · 2018: 55 · 2017: 56 · 2016: 40 · 2015: 50 · 2014: 49 · 2013: 56 · 2012: 54
- FWCI
- 17.01
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Epidemiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Effects of Exercise
- Keywords
- physical activity, myocardial infarction risk, myocardial infarction, energy expenditure, university alumni, varsity athletes, cardiorespiratory fitness, cardiovascular disease prevention
- MeSH terms
- Adult, Aged, Connecticut, Coronary Disease, Physical Exertion, Humans, Male, Middle Aged, Obesity, Physical Fitness, Retrospective Studies, Risk, Smoking, Sports
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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