The DOI matches its Crossref record.
The influence of aging on plasma sex hormones in men: the Telecom study.
Abstract
From April 1985 to July 1987, 1,408 healthy white men aged 20-60 years in Paris, France, recruited on an occupational basis, underwent a physical examination and measurements of plasma sex hormones in a cross-sectional study. Both total testosterone and estradiol showed a significant stepwise decrease with age (p less than 0.001) starting in the early adult years, while estrone did not vary. These relations of testosterone and estradiol with age remained significant after adjustment for body mass index, subscapular skinfold, and tobacco and alcohol consumptions, and they were not modified by exclusion of the men who reported chronic disease. Both the mechanism for the early decrease in testosterone and its clinical significance merit further investigation.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The decline of testosterone and DHEA (23,26,321,322) with age could be at least partially responsible for sarcopenia in older men and women.”
From Endocrine and intracrine sources of androgens in women: inhibition of breast cancer and other roles of androgens and their precursor dehydroepiandrosterone (2003) · cites this paper as [321]
Citations
Cited by
Sorted by citations
Items 101–169 of 169
Therapeutic Interventions for Age-related Muscle Wasting
Shavlakadze, T., & Grounds, M. D. (2003) · Springer eBooks · doi:10.1007/978-94-017-0283-6_9 · Cited by 22
[Physiology of androgens in adult men].
Tostain, J.-B., Rossi, D., & Martin, P. (2004) · PubMed · Cited by 12
Rakholia, M. V., Kumar, R. G., Oh, B., Ranganathan, P. R., Berga, S., Kochanek, P., & Wagner, A. (2018) · Journal of Neurotrauma · doi:10.1089/neu.2018.5782 · Cited by 13
Estrogens and Antiestrogens in the Male
Oettel, M. (1999) · Handbook of experimental pharmacology · doi:10.1007/978-3-642-60107-1_25 · Cited by 11
Smoking and male fertility: a contemporary review
Ragheb, A. M., & E.S.Jr., S. (2009) · Cited by 10
Bülow, B., Åhrén, B., Fisker, S., et al. (2003) · Clinical Endocrinology · doi:10.1046/j.1365-2265.2003.01872.x · Cited by 11
Age-Related Changes in the Male Reproductive System
Bhasin, S., Gagliano‐Jucá, T., Huang, G. T.-W., & Basaria, S. S. (2000) · Europe PMC (PubMed Central) · Cited by 18
Developmental, Estrogen Induced Infravesical Obstruction is Reversible in Adult Male Rodents
Streng, T., Lehtoranta, M., POUTANEN, M. H., et al. (2002) · The Journal of Urology · doi:10.1016/s0022-5347(05)64368-6 · Cited by 10
Associations between early alcohol and tobacco use and prolonged time to puberty in boys
Davis, E. M., Peck, J. D., Peck, B. M., & Kaplan, H. B. (2014) · Child Care Health and Development · doi:10.1111/cch.12160 · Cited by 10
The male menopause: does it exist? For: Some men need investigation and testosterone treatment
Gould, D. C. (2000) · Western Journal of Medicine · doi:10.1136/ewjm.173.2.76 · Cited by 10
Déficit Androgénique Lié à l’Age
Lejeune, H. (2001) · Andrologie · doi:10.1007/bf03034636 · Cited by 9
Effect of Risedronate on Bone Mass, Remodelling and Biomechanical Strength in Orchidectomized Rats
Díaz Curiel, M., de la Piedra, C., Romero, F. I., et al. (2008) · Hormone Research in Paediatrics · doi:10.1159/000139151 · Cited by 8
Serum sex steroids, gonadotrophins and sex hormone-binding globulin in prostatic hyperplasia
Ansari, M. A. J., Begum, D., & Islam, F. (2008) · Annals of Saudi Medicine · doi:10.5144/0256-4947.2008.174 · Cited by 10
Istvan, J. A., Buist, A. S., Hess, D. L., & Voelker, H. (1995) · Metabolism · doi:10.1016/0026-0495(95)90294-5 · Cited by 8
Free testosterone levels and implications on clinical outcomes in elderly men
Doğu, B. B., Özkayar, N., Halil, M. G., Cankurtaran, M., Ülger, Z., Tezcan, E., Gürlek, A., & Arıoğul, S. (2008) · Aging Clinical and Experimental Research · doi:10.1007/bf03324771 · Cited by 8
Gooren, L. J. (2007) · The Journal of Men s Health and Gender · doi:10.1016/j.jmhg.2007.03.003 · Cited by 7
Huuskonen, J., Väisänen, S., Kröger, H., Jurvelin, J. S., Penttila, I. M., ALHAVA, E. M., & Rauramaa, R. (2002) · Bone · doi:10.1016/s8756-3282(02)00795-0 · Cited by 7
Selected Topics in the Epidemiology of Reproductive Outcomes
Gray, R. H., & Becker, S. (2000) · Epidemiologic Reviews · doi:10.1093/oxfordjournals.epirev.a018027 · Cited by 7
Jain, A. B., Haussner, D., Hranjec, T., Butt, F., Stine, J. G., Ankola, A., Yousif, H. A., Dicristina, R., Krok, K. L., & Arenas, J. (2022) · Experimental and Clinical Transplantation · doi:10.6002/ect.2022.0132 · Cited by 6
Stanciu, I., Abboud, A., Kellman, W., Williams, D. D., & Azad, N. (2010) · The Open Andrology Journal · doi:10.2174/1876827x01002010006 · Cited by 6
“Several longitudinal and epidemiological studies reported the presence of hypogonadism in aged men [1-10].”
BackgroundAging in the Hypothalamic-Pituitary-Testicular Axis
Handelsman, D. J. (2006) · Elsevier eBooks · doi:10.1016/b978-012515400-0/50054-3 · Cited by 6
Simon, D. (2009) · Médecine des Maladies Métaboliques · doi:10.1016/s1957-2557(09)74762-5 · Cited by 5
Self-citationPharmacology, pharmacokinetics and effects/side-effects of different androgen preparations
von Eckardstein, S., & Nieschlag, E. (1998) · The Aging Male · doi:10.3109/13685539809148600 · Cited by 5
Dzhambov, A. M. (2016) · Archives of Industrial Hygiene and Toxicology · doi:10.1515/aiht-2016-67-2774 · Cited by 5
Testosterone and cardiovascular disease
Channer, K. S., & Jones, T. H. (2012) · Cambridge University Press eBooks · doi:10.1017/cbo9781139003353.011 · Cited by 5
[Age-related androgen deficiency: diagnostic work-up].
Rossi, D., & Tostain, J.-B. (2004) · PubMed · Cited by 3
Rolf, C., & Nieschlag, E. (2000) · Andrologie · doi:10.1007/978-3-662-05739-1_21 · Cited by 3
Testosterone Supplementation and Aging-associated Sarcopenia
Bhasin, S. (2004) · Research and perspectives in endocrine interactions · doi:10.1007/978-3-662-07019-2_12 · Cited by 2
Relation entre cancer et diabète : l’hyperglycémie joue t-elle un rôle ?
Simon, D. (2014) · Obésité · doi:10.1007/s11690-014-0426-9 · Cited by 2
Self-citationRolf, C., & Nieschlag, E. (2001) · Andrology · doi:10.1007/978-3-662-04491-9_21 · Cited by 2
Testosterone and Physical Function
Yalamanchi, S., Kalyani, R. R., Buta, B. J., & Dobs, A. S. (2017) · Current Sexual Health Reports · doi:10.1007/s11930-017-0136-z · Cited by 2
Rolf, C., & Nieschlag, E. (1997) · Andrology · doi:10.1007/978-3-662-03455-2_21 · Cited by 2
Ammini, A. C., Somasundaram, S., & Goswami, R. (2017) · Springer eBooks · doi:10.1007/978-981-10-3695-8_16 · Cited by 2
Physiopathologie du déficit androgénique lié à l'âge
Shakespeare, W. (2004) · Cited by 1
Changes in Health-related Parameters Associated with Sports Performance Enhancement Drugs
Wiącek, M., Trąbka, B., Tomasiuk, R., & Zubrzycki, I. Z. (2022) · International Journal of Sports Medicine · doi:10.1055/a-1960-2543 · Cited by 1
Interrelationship between Androgen Levels, Ageing, and Cognitive Functions
Joshi, H., & Parle, M. (2006) · Bioline International (Bioline International) · Cited by 1
Bhasin, S. (2005) · Wiley eBooks · doi:10.1002/9780470757826.ch21 · Cited by 1
Sexualidad y reproducción, un campo importante de la endocrinología
Becerra-Fernández, A. (2006) · Endocrinología y Nutrición · doi:10.1016/s1575-0922(06)71064-6 · Cited by 1
Gromniak, E., Syrenicz, A., Kulig, G., & Pilarska, K. (2003) · Cited by 1
Androgen Therapy in Nonendocrine Illnesses
Spratt, D. I. (2002) · Springer eBooks · doi:10.1007/978-1-4615-1161-8_18
Problema: invecchiamento maschile
Kaufman, J., Comhaire, F. H., Mahmoud, A., & MEULEMAN, E. J. H. (2010) · Springer eBooks · doi:10.1007/978-88-470-1487-9_17
Testosterone and Cardiovascular Risk Factors—Reply
Lotufo, P. A., & Manson, J. E. (2000) · Archives of Internal Medicine · doi:10.1001/archinte.160.13.2064-a
Testosterone and Cardiovascular Risk Factors
Cohen, P. G. (2000) · Archives of Internal Medicine · doi:10.1001/archinte.160.13.2064
Aspects épidémiologiques de l’association diabète et cancer
Simon, D. (2011) · Médecine des Maladies Métaboliques · doi:10.1016/s1957-2557(11)70180-8
Self-citationAndrogen Decline in the Aging Male: Making Sense of the “Male Menopause”
Shoskes, D. A. (2012) · Humana Press eBooks · doi:10.1007/978-1-61779-900-6_9
Gonadal hormones and gonadotrophins in healthy males beyond forty years.
Ansari, A. J., Kibria, S., & Islam, F. (2006) · PubMed
Neuroendocrine Regulation of Testicular Function
Kaufman, J. (2006) · Springer eBooks · doi:10.1007/3-540-33713-x_53
Lejeune, H. (1997) · Andrologie · doi:10.1007/bf03034520
“I1 existe des variat ions i n d i v i d u e l l e s i m p o r t a n t e s de la concentrat ion de testosterone, aussi bien chez les sujets jeunes que chez les sujets ~g~s, ainsi m~me si la diminution de la testos te rone se man i f e s t e p rog re s s ivemen t entre 20 et 60 ans [32], seulement --30 % des sujets ages…”
BackgroundMontori, V. M., Cunningham, G. R., Hayes, F. J., Matsumoto, A. M., Snyder, P. J., & Ronald, S. H. (2010)
Androgen Actions on Bone: Clinical Aspects
Goemaere, S., T'Sjoen, G. G., & Kaufman, J. (2009) · Humana Press eBooks · doi:10.1007/978-1-59745-459-9_17
Haren, M. T. (2005) · Adelaide Research & Scholarship (AR&S) (University of Adelaide)
Henderson, V. W. (2000)
Study of the relation between serum testosterone level and carotid atherosclerosis in elderly men
Gayar, N. H. E., Mahmoud, M., & Elabd, A. (2015) · Egyptian Journal of Obesity Diabetes and Endocrinology · doi:10.4103/2356-8062.178324
Adolescent anabolic steroid exposure alters anxiety through aggression circuits
Morrison, T. R. (2016) · Digital Repository Service (Northeastern University) · doi:10.17760/d20213405
CORRELAÇÃO DA AVALIAÇÃO CLÍNICA E LABORATORIAL NO RASTREIO DO HIPOGONADISMO MASCULINO
Fontona, F., Lavratti, V. B., Rota, C. D. B., Farneda, L. P., & Fronza, D. (2021) · FAG JOURNAL OF HEALTH (FJH) · doi:10.35984/fjh.v3i2.333
Characterisation of the ghrelinergic system in human models of neurodegenerative diseases
Carisi, M. C. (2021) · Cronfa (Swansea University) · doi:10.23889/suthesis.58915
Lopès, P., & Poudat, F.-X. (2021) · Elsevier eBooks · doi:10.1016/b978-2-294-77438-6.00005-x
Developmental, Estrogen Induced Infravesical Obstruction is Reversible in Adult Male Rodents
Streng, T., Lehtoranta, M., POUTANEN, M. H., et al. (2002) · The Journal of Urology · doi:10.1097/00005392-200211000-00111
A Better Prognosis for Obese Men with Prostate Cancer
Daniell, H. (1996) · The Journal of Urology · doi:10.1097/00005392-199601000-00078
Janjgava, S., Zerekidze, T., Uchava, L., Giorgadze, E., & Asatiani, K. (2014) · Open Access Macedonian Journal of Medical Sciences · doi:10.3889/oamjms.2014.107
(2014) · Elsevier eBooks · doi:10.1016/b978-1-907568-42-8.50016-2
Streng, T., LI, X., Lehtoranta, M., et al. (2002) · The Journal of Urology · doi:10.1097/00005392-200207000-00095
10.1016/b978-1-4160-2911-3.50020-0
(2000) · Time to knit · doi:10.1016/b978-1-4160-2911-3.50020-0
The Potential Role of Selected Endocrine Systems in Aging Processes
Nelson, J. F. (1994) · Comprehensive physiology · doi:10.1002/j.2040-4603.1994.tb01687.x
“More recently, several large epidemiological surveys (38, 70, 195) have measured testosterone during aging.”
Problème: vieillissement masculin
Kaufman, J., Comhaire, F. H., Mahmoud, A., & MEULEMAN, E. J. H. (2008) · Springer eBooks · doi:10.1007/978-2-287-72080-2_17
Detection and measurement of stress hormones with mass spectrometry
Tanner, A. (2012) · Greenwich Academic Literature Archive (University of Greenwich)
Sex Hormone Therapy for Dementia
Henderson, V. W. (2000) · Endocrine updates · doi:10.1007/978-1-4757-6507-6_3
Metadata
- Authors
- Simon, D., Preziosi, P., Barrett-Connor, E., Roger, M., Saint-Paul, M., Nahoul, K., & Papoz, L.
- Affiliations
- Inserm (FR)
- University of California San Diego (US)
- Corresponding author
- Simon, Dominique
- Venue
- American Journal of Epidemiology
- Publisher
- Oxford University Press (OUP)
- Published
- 1992-04-01
- Volume
- 135
- Issue
- 7
- Pages
- 783-791
- ISSN
- 0002-9262 (ISSN-L)
- 1476-6256
- OpenAlex
- W2290002423
- Cited by
- 166
- References
- 0
- Citations by year
- 2023: 1 · 2022: 2 · 2021: 3 · 2018: 4 · 2017: 3 · 2016: 4 · 2015: 2 · 2014: 7 · 2013: 2 · 2012: 8
- FWCI
- 2.04
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Epidemiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal and reproductive studies
- Health Sciences › Medicine › Reproductive Medicine › Sperm and Testicular Function
- Health Sciences › Medicine › Reproductive Medicine › Hypothalamic control of reproductive hormones
- Keywords
- aging, plasma sex hormones, testosterone, estradiol, estrone, men, age-related decline, body mass index, skinfold thickness, alcohol and tobacco use, chronic disease
- MeSH terms
- Adult, Aging, Alcohol Drinking, Cross-Sectional Studies, Estradiol, Estrone, Humans, Male, Middle Aged, Regression Analysis, Smoking, Testosterone, Body Mass Index
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
