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Cited by 660Advanced Glycation End Products researchAntioxidant Activity and Oxidative StressNitric Oxide and Endothelin Effects

The DOI matches its Crossref record.

Diabetes mellitus and free radicals

Wolff, S P·1993·British Medical Bulletin
DOI 10.1093/oxfordjournals.bmb.a072637
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Abstract

Diabetes mellitus is a syndrome initially characterized by a loss of glucose homeostasis. The disease is progressive and is associated with high risk of atherosclerosis, kidney and nerve damage as well as blindness. Abnormalities in the regulation of peroxide and transition metal metabolism are postulated to result in establishment of the disease as well as its longer term complications. Diabetes mellitus is associated with oxidative reactions, particularly those which are catalyzed by decompartmentalized transition metals, but their causative significance in diabetic tissue damage remains to be established.

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Crossref · 10.1093/oxfordjournals.bmb.a072637

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Metadata

Authors
Wolff, S. P.
Affiliations
University College London (GB)
Corresponding author
Wolff, S P
Venue
British Medical Bulletin
Publisher
Oxford University Press (OUP)
Published
1993
Volume
49
Issue
3
Pages
642-652
ISSN
  • 0007-1420 (ISSN-L)
  • 1471-8391
DOI
10.1093/oxfordjournals.bmb.a072637
OpenAlex
W1953115230
Cited by
660
References
0
Citations by year
2026: 2 · 2025: 9 · 2024: 2 · 2023: 6 · 2022: 12 · 2021: 9 · 2020: 13 · 2019: 17 · 2018: 11 · 2017: 15 · 2016: 22 · 2015: 32 · 2014: 35 · 2013: 29 · 2012: 31
FWCI
7.19
Type
journal article
Language
en
Open access
closed
Locations
  • British Medical Bulletin (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Clinical Biochemistry › Advanced Glycation End Products research
  • Health Sciences › Medicine › Biochemistry (medical) › Antioxidant Activity and Oxidative Stress
  • Health Sciences › Medicine › Physiology (medical) › Nitric Oxide and Endothelin Effects
Keywords
diabetes mellitus, free radicals, oxidative stress, glucose homeostasis, peroxide metabolism, atherosclerosis, diabetes complications, diabetic nephropathy, diabetic neuropathy, diabetic retinopathy
MeSH terms
Alloxan, Animals, Arginine, Diabetes Mellitus, Free Radicals, Glucose, Humans, Lysine, Metals, Oxidation-Reduction, Oxygen Consumption, Streptozocin, Lipid Peroxidation, Reactive Oxygen Species, Diabetes Complications, Rats

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