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Cited by 825

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Phylogenetic test of the molecular clock and linearized trees.

Open access
·1995·Molecular Biology and Evolution

Abstract

To estimate approximate divergence times of species or species groups with molecular data, we have developed a method of constructing a linearized tree under the assumption of a molecular clock. We present two tests of the molecular clock for a given topology: two-cluster test and branch-length test. The two-cluster test examines the hypothesis of the molecular clock for the two lineages created by an interior node of the tree, whereas the branch-length test examines the deviation of the branch length between the tree root and a tip from the average length. Sequences evolving excessively fast or slow at a high significance level may be eliminated. A linearized tree will then be constructed for a given topology for the remaining sequences under the assumption of rate constancy. We have used these methods to analyze hominoid mitochondrial DNA and drosophilid Adh gene sequences.

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Crossref · 10.1093/oxfordjournals.molbev.a040259

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Metadata

Venue
Molecular Biology and Evolution
Published
1995-09
Volume
12
Issue
5
Pages
823-33
ISSN
  • 0737-4038 (ISSN-L)
  • 1537-1719
OpenAlex
W2235442146
Cited by
825
References
3
FWCI
5.57
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Phylogenetic test of the molecular clock and linearized trees. https://app.cochat.ai/papers/10.1093/oxfordjournals.molbev.a040259
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Phylogenetic test of the molecular clock and linearized trees. (1995). Molecular Biology and Evolution. https://doi.org/10.1093/oxfordjournals.molbev.a040259

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.