The DOI matches its Crossref record; 128 of the 128 references it cites were found in a registry or an index.
Sexuality and Schizophrenia: A Review
Abstract
Sexual functioning has received little attention as an important aspect of patient care for those suffering from severe mental disorders such as schizophrenia. Yet, it has been implicated as one of the major factors contributing to noncompliance with antipsychotic medications and is documented by people with schizophrenia to be one of the areas of treatment with the most unmet needs. A stronger focus on sexuality and preventing sexual dysfunction in schizophrenia would likely be a major benefit for improving treatment. This review will describe possible mechanisms for sexual dysfunction, describe sexual disturbances that have been documented in the literature of people who have schizophrenia, and summarize and discuss assessment measures available. Moreover, a focus on second-generation antipsychotics (SGA) and their association with sexual functioning is described. Each SGA (clozapine, risperidone, olanzapine, quetiapine, ziprasidone, and aripiprazole) will be described for its prolactin effects, documented sexual disturbances associated with use, and product labeling regarding sexual function. Treatment options and psychosocial issues pertaining to sexuality also are presented.
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In the citing paper
“Sexual dysfunction in SMI patients has received little attention from clinicians (512,513).”
From Physical illness in patients with severe mental disorders. I. Prevalence, impact of medications and disparities in health care (2011) · cites this paper as [512]
In the citing paper
“Although there are relatively few systematic investigations concerning sexual disorders in schizophrenia (514), sexual dysfunction in schizophrenia is, compared to normal controls, estimated to be more frequent (515-519) and to affect 30-80% of women and 45-80% of men (512,515, 520-523).”
From Physical illness in patients with severe mental disorders. I. Prevalence, impact of medications and disparities in health care (2011) · cites this paper as [512]
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DE HERT, M., CORRELL, C. U., BOBES, J., CETKOVICH‐BAKMAS, M., COHEN, D., ASAI, I., DETRAUX, J., GAUTAM, S., MÖLLER, H., NDETEI, D. M., et al. (2011) · World Psychiatry · doi:10.1002/j.2051-5545.2011.tb00014.x · Cited by 2,488
Peuskens, J., Pani, L., Detraux, J., & De Hert, M. (2014) · CNS Drugs · doi:10.1007/s40263-014-0157-3 · Cited by 350
Antipsychotic‐Induced Hyperprolactinemia
Bostwick, J. R., Guthrie, S. K., & Ellingrod, V. L. (2008) · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy · doi:10.1592/phco.29.1.64 · Cited by 237
Side effects of atypical antipsychotics: a brief overview
Üçok, A., & Gäebel, W. (2008) · World Psychiatry · doi:10.1002/j.2051-5545.2008.tb00154.x · Cited by 240
Sexual dysfunction in schizophrenia: focus on recent evidence
Baggaley, M. (2008) · Human Psychopharmacology: Clinical and Experimental · doi:10.1002/hup.924 · Cited by 191
Metadata
- Authors
- Kelly, D. L., & Conley, R. R.
- Affiliations
- University of Maryland, Baltimore (US)
- Venue
- Schizophrenia Bulletin
- Publisher
- Oxford University Press (OUP)
- Published
- 2004-01-01
- Volume
- 30
- Issue
- 4
- Pages
- 767-779
- ISSN
- 0586-7614 (ISSN-L)
- 1745-1701
- OpenAlex
- W1978827798
- Cited by
- 164
- References
- 128
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 6 · 2023: 9 · 2022: 7 · 2021: 2 · 2020: 9 · 2019: 7 · 2018: 13 · 2017: 8 · 2016: 6 · 2015: 4 · 2014: 9 · 2013: 18 · 2012: 10
- FWCI
- 2.28
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Schizophrenia Bulletin (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
- Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
- Keywords
- schizophrenia, sexuality
- MeSH terms
- Amenorrhea, Female, Humans, Male, Prolactin, Schizophrenia, Schizophrenic Psychology, Sexual Behavior, Antipsychotic Agents
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