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Antibiotic growth promoters in agriculture: history and mode of action
Open accessAbstract
This report will review the history of antibiotic growth promoter (AGP) use in the animal industry, concerns about development of antimicrobial resistance, and response in the European Union and United States to these concerns. A brief description of the history of legislation regarding feed use of antimicrobials in Denmark and the experience of animal producers following the 1998 ban will serve to illustrate the consequences on animal performance and health of withdrawing the approval for this use. The biological basis for antibiotic effects on animal growth efficiency will consider effects on intestinal microbiota and effects on the host animal and will use the germ-free animal to illustrate effects of the conventional microflora. The probability that no single compound will replace all of the functions of antimicrobial growth promoters will be considered, and methods to consolidate and analyze the enlarging database will be discussed.
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Citations
Cited by
Food Animals and Antimicrobials: Impacts on Human Health
Marshall, B. M., & Levy, S. B. (2011) · Clinical Microbiology Reviews · doi:10.1128/cmr.00002-11 · Cited by 2,241
History of the Use of Antibiotic as Growth Promoters in European Poultry Feeds
Castanon, J. I. R. (2007) · Poultry Science · doi:10.3382/ps.2007-00249 · Cited by 1,256
In-feed antibiotic effects on the swine intestinal microbiome
Looft, T., Johnson, T. A., Allen, H. K., Bayles, D. O., Alt, D. P., Stedtfeld, R. D., Sul, W. J., Stedtfeld, T. M., Chai, B., Cole, J. R., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1120238109 · Cited by 1,072
Probiotics and prebiotics in animal feeding for safe food production
Gaggìa, F., Mattarelli, P., & Biavati, B. (2010) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2010.02.031 · Cited by 992
Intestinal microbiome is related to lifetime antibiotic use in Finnish pre-school children
Korpela, K., Salonen, A., Virta, L. J., Kekkonen, R. A., Forslund, K., Bork, P., & de Vos, W. M. (2016) · Nature Communications · doi:10.1038/ncomms10410 · Cited by 698
Metadata
- Authors
- Dibner, J. J., & Richards, J. D.
- Venue
- Poultry Science
- Publisher
- Elsevier BV
- Published
- 2005-04
- Volume
- 84
- Issue
- 4
- Pages
- 634-643
- ISSN
- 0032-5791 (ISSN-L)
- OpenAlex
- W2167179929
- Cited by
- 1,432
- References
- 0
- FWCI
- 35.02
- Type
- journal article
- Language
- en
- Open access
- hybrid
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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