Cited by 148Long-Term Effects of COVID-19COVID-19 and Mental HealthSuicide and Self-Harm Studies

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Post-COVID syndrome and suicide risk

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Sher, L·2021·QJM: An International Journal of Medicine

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Abstract

A significant number of coronavirus disease SARS-CoV-2 (COVID-19) patients continue to have symptoms related to COVID-19 after the acute phase of illness. This post-COVID condition is sometimes called ‘post-COVID syndrome’, ‘long COVID’ or ‘post-acute COVID-19’. Persistent psychiatric symptoms among COVID-19 survivors such as depression, anxiety, post-traumatic symptoms and cognitive impairment may be related to psychological factors and neurobiological injury. COVID-19 related neurological symptoms including anosmia, ageusia, dizziness, headache and seizures may persist for a long time after the acute COVID-19 illness. Many COVID-19 survivors experience persistent physical symptoms such as cough, fatigue, dyspnea and pain after recovering from their initial illness. There is a high probability that symptoms of psychiatric, neurological and physical illnesses, as well as inflammatory damage to the brain in individuals with post-COVID syndrome increase suicidal ideation and behavior in this patient population. COVID-19 survivors without post-COVID syndrome may also be at elevated suicide risk. Studies of suicidality in COVID-19 survivors are urgently needed and will be a new area of suicide research. An appropriate management of psychiatric, neurological and medical conditions may reduce suicide risk among COVID-19 survivors with or without post-COVID syndrome.

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Authors: Sher, L.
Affiliations: James J. Peters VA Medical Center (US)
Corresponding author: Sher, L
ORCID: Sher, L
Venue: QJM: An International Journal of Medicine
Publisher: Oxford University Press (OUP)
Published: 2021-01-24
Volume: 114
Issue: 2
Pages: 95-98
ISSN: 0033-5622 (ISSN-L)
1460-2725
1460-2393
DOI: 10.1093/qjmed/hcab007
PMC: PMC7928695
OpenAlex: W3122566052
Cited by: 148
References: 27
Citations by year: 2026: 3 · 2025: 9 · 2024: 27 · 2023: 38 · 2022: 45 · 2021: 26
FWCI: 16.27
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model (vor)
Locations: QJM (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Clinical Neurology › Long-Term Effects of COVID-19
Social Sciences › Psychology › Clinical Psychology › COVID-19 and Mental Health
Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
Keywords: long COVID, suicide risk, suicidal ideation, COVID-19 survivors, depression, anxiety, posttraumatic stress symptoms, cognitive impairment, neurological symptoms, anosmia, ageusia, persistent physical symptoms, neuroinflammation, psychiatric comorbidity
MeSH terms: COVID-19, Mental Disorders, Delirium, Fatigue, Headache, Humans, Severity of Illness Index, Survivors, Suicidal Ideation

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Post-COVID syndrome and suicide risk

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