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Cited by 789Systemic Lupus Erythematosus ResearchSystemic Sclerosis and Related DiseasesVasculitis and related conditions

The DOI matches its Crossref record; 111 of the 111 references it cites were found in a registry or an index.

The worldwide incidence and prevalence of systemic lupus erythematosus: a systematic review of epidemiological studies

Rees, Frances, Doherty, Michael, Grainge, Matthew J, Lanyon, Peter, Zhang, Weiya·2017·Rheumatology
DOI 10.1093/rheumatology/kex260
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Abstract

Objectives: The aim was to review the worldwide incidence and prevalence of SLE and variation with age, sex, ethnicity and time. Methods: A systematic search of MEDLINE and EMBASE search engines was carried out using Medical Subject Headings and keyword search terms for Systemic Lupus Erythematosus combined with incidence, prevalence and epidemiology in August 2013 and updated in September 2016. Author, journal, year of publication, country, region, case-finding method, study period, number of incident or prevalent cases, incidence (per 100 000 person-years) or prevalence (per 100 000 persons) and age, sex or ethnic group-specific incidence or prevalence were collected. Results: The highest estimates of incidence and prevalence of SLE were in North America [23.2/100 000 person-years (95% CI: 23.4, 24.0) and 241/100 000 people (95% CI: 130, 352), respectively]. The lowest incidences of SLE were reported in Africa and Ukraine (0.3/100 000 person-years), and the lowest prevalence was in Northern Australia (0 cases in a sample of 847 people). Women were more frequently affected than men for every age and ethnic group. Incidence peaked in middle adulthood and occurred later for men. People of Black ethnicity had the highest incidence and prevalence of SLE, whereas those with White ethnicity had the lowest incidence and prevalence. There appeared to be an increasing trend of SLE prevalence with time. Conclusion: There are worldwide differences in the incidence and prevalence of SLE that vary with sex, age, ethnicity and time. Further study of genetic and environmental risk factors may explain the reasons for these differences. More epidemiological studies in Africa are warranted.

Overview

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Crossref · 10.1093/rheumatology/kex260

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111 of 111 references verified0 citation errors · 0 not checkable

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  • Differences in ethnicity between the SARD-BDB and Toronto cohorts may impact results such as incidence, prevalence, and mortality rates.

    “Such differences between two groups of patients may also impact results such as the incidence, prevalence and mortality rates (76–79).”

    From Autoantibodies in Systemic Lupus Erythematosus Target Mitochondrial RNA (2019) · cites this paper as [79]

Citations

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Research works printed but not linked: 2

  1. 2002, Systemic lupus erythematosus in Martinique, French West Indies: an epidemiology-based study, Rev Med Intern, 23, 21
  2. 2004, Solar UV-B radiation is linked to the geographic variation of mortality from systemic lupus erythematosus in the USA, Lupus, 13, 281

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Metadata

Authors
Rees, F., Doherty, M., Grainge, M. J., Lanyon, P., & Zhang, W.
Affiliations
  • Nottingham University Hospitals NHS Trust (GB)
  • University of Nottingham (GB)
ORCID
Venue
Rheumatology
Publisher
Oxford University Press (OUP)
Published
2017-08-09
Volume
56
Issue
11
Pages
1945-1961
ISSN
  • 1462-0324 (ISSN-L)
  • 1462-0332
DOI
10.1093/rheumatology/kex260
OpenAlex
W2744484065
Cited by
789
References
111
Citations by year
2026: 60 · 2025: 69 · 2024: 92 · 2023: 97 · 2022: 121 · 2021: 129 · 2020: 106 · 2019: 82 · 2018: 27 · 2017: 2
FWCI
9.50
Type
journal article
Language
en
Open access
closed
Locations
  • Lara D. Veeken (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Rheumatology › Systemic Lupus Erythematosus Research
  • Health Sciences › Medicine › Rheumatology › Systemic Sclerosis and Related Diseases
  • Health Sciences › Medicine › Rheumatology › Vasculitis and related conditions
Keywords
systemic lupus erythematosus, incidence, prevalence, global epidemiology, sex differences, age differences, ethnic differences, temporal trends, Black ethnicity, North America, Africa
MeSH terms
Africa, Asia, Central America, Europe, Humans, Lupus Erythematosus, Systemic, North America, South America, Incidence, Prevalence, Age Distribution, Sex Distribution, Australasia

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