The DOI matches its Crossref record; 52 of the 52 references it cites were found in a registry or an index.
Intellectual Deficits in First-Episode Schizophrenia: Evidence for Progressive Deterioration
Open accessAbstract
The developmental processes leading to neuropsychological deficits in schizophrenia are poorly understood. Both early developmental defects and subsequent deterioration may occur. Intelligence test profiles are often used to estimate premorbid ability and deterioration from prior levels of functioning. These characteristics were assessed in samples of first-episode (n = 51) and chronic (n = 50) schizophrenic patients. Although the groups showed few differences on tests to estimate premorbid intellectual ability, the chronic group performed worse on measures considered sensitive to deterioration. Dextral (right-handed) patients tended to have better performance; this effect was marked in the first-episode sample, especially on verbal tests. Male patients showed more evidence of deterioration than female patients. Subgroups differing in the time course of premorbid social dysfunction also differed in intelligence test profiles, suggesting that estimates of social and cognitive deterioration may have concurrent validity. The results support the hypothesis that patients differ in the course of cognitive decline and suggest that deterioration of function may follow the onset of overt psychosis in some patients. Prospective longitudinal studies of first-episode schizophrenic patients could directly test this hypothesis.
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Cites
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Cited by
Neurocognitive deficit in schizophrenia: A quantitative review of the evidence.
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Neurocognition in first-episode schizophrenia: a meta-analytic review.
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Neuropsychological deficits in neuroleptic naive patients with first-episode schizophrenia
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Neuropsychology of First-Episode Schizophrenia: Initial Characterization and Clinical Correlates
Bilder, R. M., Goldman, R. S., Robinson, D., Reiter, G., Bell, L., Bates, J. A., Pappadopulos, E., Willson, D. F., Alvir, J. M. J., Woerner, M. G., et al. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.4.549 · Cited by 906
Self-citation
Metadata
- Authors
- Bilder, R. M., Lipschutz-Broch, L., Reiter, G., Geisler, S. H., Mayerhoff, D. I., & Lieberman, J. A.
- Venue
- Schizophrenia Bulletin
- Publisher
- Oxford University Press (OUP)
- Published
- 1992-01-01
- Volume
- 18
- Issue
- 3
- Pages
- 437-448
- ISSN
- 0586-7614 (ISSN-L)
- 1745-1701
- OpenAlex
- W2162052901
- Cited by
- 285
- References
- 52
- FWCI
- 7.17
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Bilder, R. M., Lipschutz-Broch, L., Reiter, G., Geisler, S. H., Mayerhoff, D. I., & Lieberman, J. A. (1992). Intellectual Deficits in First-Episode Schizophrenia: Evidence for Progressive Deterioration. Schizophrenia Bulletin. https://doi.org/10.1093/schbul/18.3.437
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.