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Cited by 266

The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.

The Use of Exogenous Melatonin in Delayed Sleep Phase Disorder: A Meta-analysis

Open access
van Geijlswijk, Ingeborg M., Korzilius, Hubert P. L. M., Smits, Marcel G.·2010·Sleep
DOI 10.1093/sleep/33.12.1605
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Abstract

STUDY OBJECTIVES: To perform a meta-analysis of the efficacy and safety of exogenous melatonin in advancing sleep-wake rhythm in patients with delayed sleep phase disorder. DESIGN: Meta analysis of papers indexed for PubMed, Embase, and the abstracts of sleep and chronobiologic societies (1990-2009). PATIENTS: Individuals with delayed sleep phase disorder. INTERVENTIONS: Administration of melatonin. MEASUREMENTS AND RESULTS: A meta-analysis of data of randomized controlled trials involving individuals with delayed sleep phase disorder that were published in English, compared melatonin with placebo, and reported 1 or more of the following: endogenous melatonin onset, clock hour of sleep onset, wake-up time, sleep-onset latency, and total sleep time. The 5 trials including 91 adults and 4 trials including 226 children showed that melatonin treatment advanced mean endogenous melatonin onset by 1.18 hours (95% confidence interval [CI]: 0.89-1.48 h) and clock hour of sleep onset by 0.67 hours (95% CI: 0.45-0.89 h). Melatonin decreased sleep-onset latency by 23.27 minutes (95% CI: 4.83 -41.72 min). The wake-up time and total sleep time did not change significantly. CONCLUSIONS: Melatonin is effective in advancing sleep-wake rhythm and endogenous melatonin rhythm in delayed sleep phase disorder.

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Metadata

Authors
van Geijlswijk, I. M., Korzilius, H. P. L. M., & Smits, M. G.
Venue
Sleep
Publisher
Oxford University Press (OUP)
Published
2010-12
Volume
33
Issue
12
Pages
1605-1614
ISSN
  • 0161-8105 (ISSN-L)
  • 1550-9109
DOI
10.1093/sleep/33.12.1605
OpenAlex
W1808619209
Cited by
266
References
11
FWCI
0.92
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: The Use of Exogenous Melatonin in Delayed Sleep Phase Disorder: A Meta-analysis. https://app.cochat.ai/papers/10.1093/sleep/33.12.1605
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van Geijlswijk, I. M., Korzilius, H. P. L. M., & Smits, M. G. (2010). The Use of Exogenous Melatonin in Delayed Sleep Phase Disorder: A Meta-analysis. Sleep. https://doi.org/10.1093/sleep/33.12.1605

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