The DOI matches its Crossref record; 71 of the 71 references it cites were found in a registry or an index.
Fatigue in Multiple Sclerosis: Mechanisms, Evaluation, and Treatment
Open accessAbstract
Among patients with multiple sclerosis (MS), fatigue is the most commonly reported symptom, and one of the most debilitating. Despite its high prevalence and significant impact, fatigue is still poorly understood and often under-emphasized because of its complexity and subjective nature. In recent years, an abundance of literature from specialists in sleep medicine, neurology, psychiatry, psychology, physical medicine and rehabilitation, and radiology have shed light on the potential causes, impact, and treatment of MS-related fatigue. Though such a diversity of contributions clearly has advantages, few recent articles have attempted to synthesize this literature, and existing overviews have focused primarily on potential causes of fatigue rather than clinical evaluation or treatment. The aims of this review are to examine, in particular for sleep specialists, the most commonly proposed primary and secondary mechanisms of fatigue in MS, tools for assessment of fatigue in this setting, and available treatment approaches to a most common and challenging problem.
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Cites
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Cited by
Ortelli, P., Ferrazzoli, D., Sebastianelli, L., Engl, M., Romanello, R., Nardone, R., Bonini, I., Koch, G., Saltuari, L., Quartarone, A., et al. (2021) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2020.117271 · Cited by 298
Effects of Exercise Training on Fatigue in Multiple Sclerosis: A Meta-Analysis
Pilutti, L. A., Greenlee, T. A., Motl, R. W., Nickrent, M. S., & Petruzzello, S. J. (2013) · Psychosomatic Medicine · doi:10.1097/psy.0b013e31829b4525 · Cited by 271
Ulrichsen, K. M., Kaufmann, T., Dørum, E. S., Kolskår, K. K., Richard, G., Alnæs, D., Arneberg, T. J., Westlye, L. T., & Nordvik, J. E. (2016) · Frontiers in Psychology · doi:10.3389/fpsyg.2016.00912 · Cited by 86
Fatigue at time of CIS is an independent predictor of a subsequent diagnosis of multiple sclerosis
Runia, T. F., Jafari, N., Siepman, D. A. M., & Hintzen, R. Q. (2015) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp-2014-308374 · Cited by 70
Snow, N. J., Wadden, K. P., Chaves, A. R., & Ploughman, M. (2019) · Neural Plasticity · doi:10.1155/2019/6430596 · Cited by 56
Metadata
- Authors
- Braley, T. J., & Chervin, R. D.
- Venue
- Sleep
- Publisher
- Oxford University Press (OUP)
- Published
- 2010-08
- Volume
- 33
- Issue
- 8
- Pages
- 1061-1067
- ISSN
- 0161-8105 (ISSN-L)
- 1550-9109
- OpenAlex
- W185235087
- Cited by
- 403
- References
- 71
- FWCI
- 5.19
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
