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Genetic and Environmental Determination of Human Sleep
Abstract
Self-reported sleep data from 2238 monozygotic and 4545 dizygotic adult twin pairs indicated a significant hereditary effect on sleep length [overall heritability estimate (h2 = 0.44)] and on sleep quality (h2 = 0.44). When the data were examined in subgroups defined by sex, age (18-24 years and 25 or more years of age), and cohabitation status of the twin pair, the highest heritability estimates for sleep length were for twins living together aged 25 or older. For twins living apart the heritability estimates were statistically significant in all women and men aged 25 or older. For sleep quality significant heritability estimates were found for all groups except women living together.
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“Systematic twin studies using large samples indicate that genetic differences account for 30 -45% of the variance in subjective sleep quality and sleep disturbances (186, 526, 889) and for ϳ50% in physiological measures of sleep stages (137,737,738).”
From About Sleep's Role in Memory (2013) · cites this paper as [889]
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“Twin studies show sleep duration heritability between 31% and 55%, suggesting substantial genetic influences on sleep need.23,48,49”
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Metadata
- Authors
- Partinen, M., Kaprio, J., Koskenvuo, M., Putkonen, P., & Langinvainio, H.
- Affiliations
- University of Helsinki (FI)
- Venue
- Sleep
- Publisher
- Oxford University Press (OUP)
- Published
- 1983-09
- Volume
- 6
- Issue
- 3
- Pages
- 179-185
- ISSN
- 0161-8105 (ISSN-L)
- 1550-9109
- OpenAlex
- W2402965734
- Cited by
- 257
- References
- 0
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 7 · 2023: 3 · 2022: 4 · 2021: 13 · 2020: 8 · 2019: 14 · 2018: 6 · 2017: 12 · 2016: 12 · 2015: 7 · 2014: 14 · 2013: 26 · 2012: 12
- FWCI
- 0.56
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- SLEEP (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Academy of Finland
- Suomen Kulttuurirahasto
- Medical Research Council
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
- Keywords
- sleep quality, heritability, monozygotic twins, dizygotic twins, twin pairs, genetic factors, environmental factors, sex differences, age differences, cohabitation status
- MeSH terms
- Adolescent, Adult, Environment, Female, Genetics, Humans, Male, Pregnancy, Sleep, Time Factors, Twins, Twins, Dizygotic, Twins, Monozygotic
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