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Cited by 13

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Early vs delayed insertion of penile prosthesis in patients with refractory priapism: a systematic review and meta-analysis

Elmarasi, Mohamed, Alsaeedi, Ahmad, Elmakaty, Ibrahim, Elsayed, Basel, Khalil, Ibrahim A, Aldeeb, Maya, Khalafalla, Kareim, Al Kubaisi, Khalid, Arafa, Mohamed, Majzoub, Ahmed·2024·Sexual Medicine Reviews
DOI 10.1093/sxmrev/qeae007
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Abstract

Introduction: Refractory priapism, characterized by persistent and prolonged painful erections despite initial treatment maneuvers, can significantly impair erectile function secondary to ischemia-induced corporal tissue fibrosis. These patients will likely require subsequent penile prosthesis (PP) surgery to regain sexual activity, yet consensus regarding the optimal timing of implantation remains lacking. Objectives: To evaluate and compare the clinical outcomes associated with early vs delayed PP implantation in individuals with priapism-induced erectile dysfunction (ED). Methods: We included studies that focused on refractory priapism leading to ED and its management with PP implantation. We assessed cohort study bias with a risk-of-bias tool and case series bias with the modified Newcastle-Ottawa Scale. Pooled odds ratios (ORs) were calculated by a fixed-effect model. Results: We included 9 studies, comprising 4 cohort studies and 5 case series, involving a total of 278 patients. Total complications were higher in the delayed group (OR, 4.16; 95% CI, 2.77-6.26). Fibrosis was significantly more pronounced in the delayed group (OR, 118.18; 95% CI, 20.06-696.32). The odds of erosion, infections, and penile injury did not show statistically significant differences between the groups (OR, 2.52 [95% CI, 0.67-9.49], 0.89 [0.38-2.10], 1.83 [0.79-4.26], respectively). Patients’ satisfaction resulted in a pooled OR of 0.15 (95% CI, 0.04-0.49) in favor of the early PP insertion group. Conclusion: The results from this study favor an early approach to ED (within 30 days) following ischemic priapism. However, it is important to consider patients’ preferences, values, and psychological factors to make an informed decision.

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Research works printed but not linked: 27

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Cited by

Metadata

Authors
Elmarasi, M., Alsaeedi, A., Elmakaty, I., Elsayed, B., Khalil, I. A., Aldeeb, M., Khalafalla, K., Al Kubaisi, K., Arafa, M., & Majzoub, A.
Venue
Sexual Medicine Reviews
Publisher
Oxford University Press (OUP)
Published
2024-03-11
Volume
12
Issue
3
Pages
528-536
ISSN
  • 2050-0513
  • 2050-0521
DOI
10.1093/sxmrev/qeae007
Cited by
13
References
3
Language
en
Licence
creativecommons.org/licenses/by/4.0/ (vor)

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