The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Enzymatic control of pigmentation in mammals
Abstract
Visible pigmentation in mammals results from the synthesis and distribution of melanin in the skin, hair bulbs, and eyes. The melanins are produced in melanocytes and can be of two basic types: eumelanins, which are brown or black, and phaeomelanins, which are red or yellow. In mammals typically there are mixtures of both types. The most essential enzyme in this melanin bio‐synthetic pathway is tyrosinae and it is the only enzyme absolutely required for melanin production. However, recent studies have shown that mammalian melanogenesis is not regulated solely by tyrosinase at the enzymatic level, and have identified additional melanogenic factors that can modulate pigmentation in either a positive or negative fashion. In addition, other pigment‐specific genes that are related to tyrosinase have been cloned which encode proteins that apparently work together at the catalytic level to specify the quantity and quality of the melanins synthesized. Future research should provide a greater understanding of the enzymatic interactions, processing, and tissue specificity that are important to pigmentation in mammals.—Hearing, V. J.; Tsukamoto, K. Enzymatic control of pigmentation in mammals. FASEB J. 5: 2902‐2909; 1991.
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Cites
Effect of metal ions on the rearrangement of dopachrome
PALUMBO, A., DISCHIA, M., MISURACA, G., & PROTA, G. (1987) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/0304-4165(87)90110-3 · Cited by 158
Giebel, L. B., Strunk, K. M., King, R. A., Hanifin, J. M., & Spritz, R. A. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.9.3255 · Cited by 74
Melanin Monomers Within Coated Vesicles and Premelanosomes in Melanin Synthesizing Cells
Hatta, S., Mishima, Y., Ichihashi, M., & Ito, S. (1988) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12464454 · Cited by 55
Cited by
Melanin pigmentation in mammalian skin and its hormonal regulation
Slominski, A., Tobin, D. J., Shibahara, S., & Wortsman, J. (2004) · Physiological Reviews · doi:10.1152/physrev.00044.2003 · Cited by 2,015
Human skin pigmentation: Melanocytes modulate skin color in response to stress
Costin, G.-E., & Hearing, V. J. (2007) · The FASEB Journal · doi:10.1096/fj.06-6649rev · Cited by 976
Self-citationA gene for the mouse pink-eyed dilution locus and for human type II oculocutaneous albinism
Rinchik, E. M., Bultman, S. J., Horsthemke, B., Lee, S.-T., Strunk, K. M., Spritz, R. A., Avidano, K. M., Jong, M. T. C., & Nicholls, R. D. (1993) · Nature · doi:10.1038/361072a0 · Cited by 414
Mitogenic and melanogenic stimulation of normal human melanocytes by melanotropic peptides
Abdel-Malek, Z., Swope, V. B., Suzuki, I., Akcali, C., Harriger, M. D., Boyce, S. T., Urabe, K., & Hearing, V. J. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.5.1789 · Cited by 377
Self-citationTyrosinase/catecholoxidase activity of hemocyanins: structural basis and molecular mechanism
Decker, H., & Tuczek, F. (2000) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(00)01602-9 · Cited by 377
Metadata
- Authors
- Hearing, V. J., & Tsukamoto, K.
- Venue
- The FASEB Journal
- Publisher
- Wiley
- Published
- 1991-11
- Volume
- 5
- Issue
- 14
- Pages
- 2902-2909
- ISSN
- 0892-6638 (ISSN-L)
- 1530-6860
- OpenAlex
- W1644644959
- Cited by
- 761
- References
- 3
- FWCI
- 10.53
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
