The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.
Endothelial cell‐to‐cell junctions
Abstract
The endothelium forme the main barrier to the passage of macromolecules and circulating cells from blood to tissues. Endothelial permeability is in large part regulated by intercellular junctions. These are complex structures formed by transmembrane adhesive molecules linked to a network of cytoplasmic/cytoskeletal proteins. At least four different types of endothelial junctions have been described: tight junctions, gap junctions, adherence junctions and syndesmos. lítese organelles have some features and components in common with epithelial cells but there are also some that are specific for the endothelium. The mechanisms that regulate the opening and closing of endothelial junctions are still obscure. It is conceivable that inflammatory agents increase permeabilty by binding to specific receptors generating intracellular signals, which in turn cause cytoskeletal reorganization and opening of interen‐ dothelial cell gaps. Endothelial junctions also control leukocyte extravasation. Once leukocytes have adhered to the endothelium, a coordinated opening of interendothelial cell junctions occurs. The mechanism by which this takes place is unknow, but it might present characteristics similar to that triggered by soluble mediators.—Dejana, E., Corada, M., Lampugnani, M. G. Endothelial cell‐to‐cell junctions. FASEBJ ., 9, 910‐918 (1995)
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Cites
Cadherin Cell Adhesion Receptors as a Morphogenetic Regulator
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Occludin: a novel integral membrane protein localizing at tight junctions.
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Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis.
Connolly, D. T., Heuvelman, D. M., Nelson, R., Olander, J. V., Eppley, B. L., Delfino, J. J., Siegel, N. R., Leimgruber, R. M., & Feder, J. (1989) · Journal of Clinical Investigation · doi:10.1172/jci114322 · Cited by 1,265
PECAM-1 is required for transendothelial migration of leukocytes.
Muller, W. A., Weigl, S. A., Deng, X., & Phillips, D. M. (1993) · The Journal of experimental medicine · doi:10.1084/jem.178.2.449 · Cited by 1,152
From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion
Kemler, R. (1993) · Trends in Genetics · doi:10.1016/0168-9525(93)90250-l · Cited by 982
PECAM-1 (CD31) Cloning and Relation to Adhesion Molecules of the Immunoglobulin Gene Superfamily
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A novel endothelial-specific membrane protein is a marker of cell-cell contacts.
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Self-citationDevelopment of the blood-brain barrier
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Cited by
Origins of circulating endothelial cells and endothelial outgrowth from blood
Lin, Y., Weisdorf, D. J., Solovey, A., & Hebbel, R. P. (2000) · Journal of Clinical Investigation · doi:10.1172/jci8071 · Cited by 1,531
Michiels, C. (2003) · Journal of Cellular Physiology · doi:10.1002/jcp.10333 · Cited by 773
Control of hair growth and follicle size by VEGF-mediated angiogenesis
Yano, K., Brown, L. F., & Detmar, M. (2001) · Journal of Clinical Investigation · doi:10.1172/jci11317 · Cited by 710
Vascular endothelial–cadherin is an important determinant of microvascular integrity invivo
Corada, M., Mariotti, M., Thurston, G., Smith, K., Kunkel, R., Brockhaus, M., Lampugnani, M. G., Martin-Padura, I., Stoppacciaro, A., Ruco, L., et al. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.17.9815 · Cited by 676
Self-citationMedina-Leyte, D. J., Zepeda-García, O., Domínguez-Pérez, M., González-Garrido, A., Villarreal-Molina, T., & Jacobo-Albavera, L. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22083850 · Cited by 623
Metadata
- Authors
- Dejana, E., Corada, M., & Lampugnani, M. G.
- Venue
- The FASEB Journal
- Publisher
- Wiley
- Published
- 1995-07
- Volume
- 9
- Issue
- 10
- Pages
- 910-918
- ISSN
- 0892-6638 (ISSN-L)
- 1530-6860
- OpenAlex
- W1861095564
- Cited by
- 477
- References
- 27
- FWCI
- 17.28
- Type
- journal article
- Language
- en
- Open access
- closed
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