Amyloid beta oligomers induce impairment of neuronal insulin receptors
Zhao, Wei‐Qin, De Felice, Fernanda G., Fernandez, Sara, Chen, Hui, Lambert, Mary P., Quon, Michael J., Krafft, Grant A., Klein, William L.·2008·The FASEB Journal
Cited by (590)
Items 501–590 of 590
- Risk Factors for Alzheimer’s DiseaseA. A. Farooqui · 2017 · Elsevier eBooks
- Heat Therapy with Relevance to the Reversal of NAFLD and DiabetesIan James Martins · 2017 · Diabetes & Metabolic Disorders
- Relation mutuelle entre Tau et signalisation centrale de l’insulineAurélie Joly‐Amado, Maud Gratuze, Hamza Benderradji, Didier Vieau, Luc Buée, David L Blum · 2018 · médecine/sciences
- Association of circadian dysregulation with retinal degeneration and Alzheimer’s disease: a special focus on Muller glial cellsGlori Das, Thomas E. Milner · 2024 · Frontiers in Photonics
- T-regulatory cells and extracellular vesicles in Alzheimer’s disease: New therapeutic concepts and hypothesesRicardo Augusto Leoni De Sousa, Bruno Ferreira Mendes · 2024 · Brain Research
- Brain insulin resistance as an early target to attenuate neuroinflammation, oxidative stress and proteinopathies in Alzheimer’s disease: A systematic review of five natural productsReem A. Mohamed, Radwa H. Abdelaziz, Mohamed S. Mohamed, Nayra H. Ahmed, Rouz M. Ahmed · 2025 · Next research.
- Oleanolic Acid and Alzheimer’s Disease: Mechanistic Hypothesis of Therapeutic PotentialJuan Manuel Espinosa-Cabello, Ángel Fernández‐Aparicio, Emilio González‐Jiménez, Gisela Perez-Muñoz, José M. Castellano, Javier S. Perona · 2026 · Applied Sciences
- Acute amyloid-β exposure disrupts insulin signaling in hCMEC/D3 blood–brain barrier endothelial cellsDouglas A. Nelson, Suresh Kumar Swaminathan, Vaishnavi Veerareddy, Hannah S. Seo, Samira M. Azarin, Krishna R. Kalari, Karunya K. Kandimalla · 2026 · Fluids and Barriers of the CNS
- Glucagon-Like Peptide-1 Signaling in Learning and Memory: Evidence, Mechanisms, and Therapeutic ImplicationsAlexander G. Bashaw, Ciorana Roman-Ortiz, Serena X. Gao, Lindsey A. Schier, Tito Borner, Scott E. Kanoski · 2026 · Biological Psychiatry
- Neurochemical Aspects of Alzheimer DiseaseA. A. Farooqui · 2016 · Springer eBooks
- Glucose, glycolysis, and neurodegenerative disordersPatrícia Coelho, Ana Cristina Rego · 2023 · Elsevier eBooks
- Action and Interaction of Amyloid-β and Insulin on Dopamine Release and Reuptake in the Dorsal Lateral Striatum of RatsValery N. Mukhin, Ivan R. Borovets, Vadim V. Sizov, В. М. Клименко · 2024 · Journal of Evolutionary Biochemistry and Physiology
- Efficacy of Stem Cell-derived Extracellular Vesicles in the Treatment of Alzheimer's Disease Model Mice: A Systematic Review and Meta-analysisQinpin Zheng, Sensen Wang, Tian Wang, Guirong Zhang · 2025 · Current Stem Cell Research & Therapy
- Targeting Aβ Receptors to Modify Alzheimer’s Disease ProgressionLaura T. Haas, Stephen M. Strittmatter · 2016 · Elsevier eBooks
- Oxidative Stress, Metabolic Syndrome and Alzheimer’s DiseaseDanira Toral-Ríos, Karla Carvajal, Bryan Víctor Phillips-Farfán, Luz Camacho, Victoria Campos‐Peña · 2016 · Springer eBooks
- Cerebral insulin resistance: current concepts of the pathogenesis and possible therapeutic strategiesRadiy Germanovich Esin, И Х Хайруллин, Oleg Radievich Esin · 2018 · S S Korsakov Journal of Neurology and Psychiatry
- Effects of Chronic Administration of Pioglitazone on Learning and Memory in Rat Model of Streptozotocin-induced Alzheimer’s DiseaseEhsan Aali, Mohammad Hossein Esmaeili, Sead Shima Mahmodi, Poriea Solimani · 2020 · The Journal of Qazvin University of Medical Sciences
- Brain Hydrophobic Peptides Antagonists of Neurotoxic Amyloid β Peptide Monomers/Oligomers–Protein InteractionsCarlos Gutiérrez‐Merino · 2023 · International Journal of Molecular Sciences
- MicroRNA cargo in neuron‐derived vesicles as peripheral biomarkers of brain insulin dysregulationJacob Alexander Cleary, Ashish Kumar, Yixin Su, Sangeeta Singh, Fang‐Chi Hsu, Suzanne Craft, William Harrison, Christopher Dirk Keene, Marjorie J. Howard, Kathleen M. Hayden et al. · 2025 · Alzheimer s & Dementia
- Insulin resistance as a mediator of physical activity's effects on beta-amyloid accumulation and tau phosphorylation: A scoping reviewMichael G Slee, Joanne Scotney, Stephanie Ruth Rainey‐Smith, Kirk I. Erickson, Hamid Reza Sohrabi, Giuseppe Verdile, Belinda M. Brown · 2025 · Ageing Research Reviews
- Proposed unified model of late-onset Alzheimer's disease: Chronic astrocytic and neuronal bioenergetic failureJames P Garrahy · 2025 · Journal of Alzheimer s Disease
- Fisetin targets multiple signaling pathways to suppress microglia-mediated neuroinflammation and cognitive decline in Alzheimer's diseaseYu-Ting Dai, Qian Chen, Yan-Dong Ma, Hang Liu, Handan Zheng, Yi-Yi Zhu, Lei Gao, Qin Zhao, Jie-Lin Bai, Yu-Chen Fan et al. · 2026 · Neuropharmacology
- Combating ageing beyond the cell: Emerging roles of extracellular proteostasisSiddharth R. Venkatesh, Ivan Gallotta, Bolanle Fatimat Olabiyi, Yoon Hee Choi, Sarah Inglesfield, Janet R. Kumita, Collin Y. Ewald, Della C. David · 2026 · FEBS Journal
- Genetic Risk Factors: Their Function and Comorbidities in Alzheimer′s DiseaseMikko O. Hiltunen, Lars Bertram, Aleister J. Saunders · 2011 · International Journal of Alzheimer s Disease
- Biological Targeting and Activity of Pre-fibrillar Aβ AssembliesKyle C. Wilcox, Jason E. Pitt, Adriano Silva Sebollela, Helen Martirosova, Pascale N. Lacor, William L. Klein · 2011 · Springer eBooks
- The effect of metformin on memory retention of inhibitory avoidance learning in streptozotocin-induced rat model of alzheimer’s diseaseMohammad Hossein Esmaeili, Mafe Esmaeili Mahin · 2015 · KAUMS Journal
- Amyloid Hypothesis: Molecular and Cellular Aspects of ToxicityRakez Kayed, Cristian A. Lasagna‐Reeves · 2013 · Modecular medicine and medicinal
- Diet, Abeta Oligomers and Defective Insulin and Neurotrophic Factor Signaling in Alzheimer’s DiseaseGreg M. Cole, Qiu‐Lan Ma, Fusheng Yang, Atul M. Deshpande, Oliver J. Ubeda, Sally Ann Frautschy · 2010 · Research and perspectives in Alzheimer's disease
- Effects of Long Term Consumption of High Calorie Diet on Neurological DisordersA. A. Farooqui · 2015 · Springer eBooks
- Type 2 diabetes mellitus, drug addiction, bipolar disorder and epilepsy display overlapping aetiopathogenic mechanisms: Implication for prevention and pharmacotherapyS. E. Oriaifo · 2015 · International Research Journal of Medicine and Medical Sciences
- An Investigation on the Fundamental Interaction between Abeta Peptides and the AT-Rich DNALi Na Zhao, Jie Zheng, Lock Yue Chew, Yuguang Mu · 2015 · The Journal of Physical Chemistry B
- NEUROINFLAMMATION AND INSULIN RESISTANCE IN ALZHEIMER’S DISEASEПетрова М. М, Удк, При Болезни Альцгеймера · 2014 · CyberLeninK (CyberLeninka)
- Insulin resistance and Alzheimer’s diseaseA. A. Farooqui · 2020 · Elsevier eBooks
- Inflammation and insulin resistance in Alzheimer’s diseaseYuval Nash, Dan Frenkel · 2020 · Elsevier eBooks
- Roundoc Rx: Inflammation and Functional Medicine Interventions: Part 1—Inflammation and Chronic DiseaseROBERT L. ROUNTREE · 2010 · Alternative and Complementary Therapies
- Protective Roles of the Incretin Hormones Glucagon-Like Peptide-1 and Glucose-Dependent Insolinotropic Polypeptide Hormones in NeurodegenerationChristian Hölscher · 2011 · InTech eBooks
- Glucose facilitates Aβ oligomerization and tau phosphorylation in C. elegans model of Alzheimer’s diseaseWaqar Ahmad · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
- Protein Misfolding and DiseaseJohanna C. Scheinost, Grant E. Boldt, Paul Wentworth · 2012 · Chemical biology
- Complications of Diabetes Mellitus and their PathophysiologyRichard F. Dods · 2013
- Roles of Glucagon‐Like Peptide and Glucose‐Dependent Insolinotropic Polypeptide Hormones in Brain Function and NeurodegenerationChristian Hölscher · 2012 · Wiley eBooks
- The Janus Face of Insulin in BrainAna Isabel Duarte, Emanuel Candeias, Sónia C. Correia, Renato X. Santos, Cristina Carvalho, Susana Cardoso, Ana I. Plácido, Maria S. Santos, Catarina Resende Oliveira, Paula Isabel Moreira · 2013 · Wiley eBooks
- Protein Misfolding and DiseaseJohanna C. Scheinost, Grant E. Boldt, Paul Wentworth · 2008 · Wiley eBooks
- Modulation of Cognition by Insulin and Aging: Implications for Alzheimer DiseaseMaite Solas, María Javier Ramírez · 2013 · Wiley eBooks
- Physico-chemical characterization of beta-amyloid oligomers and study of their function in biological processes at molecular levelDóra Simon · 2011 · SZTE Repository of Dissertations (University of Szeged)
- Type 2 Diabetes and DementiaMark W. J. Strachan · 2011 · Springer eBooks
- Molecular changes during the development of Alzheimer's diseaseKerstin T.S. Wirz · 2013 · Data Archiving and Networked Services (DANS)
- Multi-tasking, Executive Function, and Functional Abilities in Older Adults with Type 2 Diabetes MellitusJASON L. RUCKER · 2014 · KU ScholarWorks (The University of Kansas)
- Review article: ROLE OF ANTI-DIABETIC DRUGS AS THERAPEUTIC AGENTS IN ALZHEIMER'S DISEASESyed Mohd, Danish Raza Rizvi, Sibhghatulla Shaikh, Shah Mohammad Abbas Waseem, Shazi Shakil, Adel Mohammed Abuzenadah, Deboshree Biswas, Shams S. M. Tabrez, Mohammad Amjad Kamal, Saudi Arabia · 2015
- Inflammation, Defective Insulin Signaling, and Mitochondrial Dysfunction as Common Molecular Denominators Connecting Type 2 Diabetes toFernanda G. De Felice, Sergio Teixeira Ferreira · 2014
- Investigation on the mechanism of amyloid beta peptides oligomerization and the process for its inhibitionLi Na Zhao · 2013
- Using TUDCA to treat Alzheimer's disease after pathology onset in APP/PS1 micePedro Dionísio · 2014 · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)
- Señalización por insulina en el cerebro y su participación en la enfermedad de AlzheimerDavid Heras-Sandoval, Clorinda Arias · 2009
- THE EFFECT OF METFORMIN ON SPATIAL LEARNING AND MEMORY IN STREPTOZOTOCIN RAT MODEL OF ALZHEIMER'S DISEASEMaryam Khosravi, Mohammad Hossein Esmaeili, Mafe Esmaeili Mahin · 2014
- Using TUDCA to treat Alzheimer's disease after pathology onset in APP/PS1 miceFaculdade De Farmácia · 2014
- Effects of Curcumin on Oxidative Stress in Animal Models and Patients with Alzheimer DiseaseA. A. Farooqui · 2016 · Springer eBooks
- Mechanisms of amyloid-beta cytotoxicity in hippocampal network function : rescue strategies in Alzheimer's diseaseFiroz Roshan Kurudenkandy · 2016 · Figshare
- Type II Diabetes and Metabolic Syndrome as Risk Factors for Alzheimer’s DiseaseA. A. Farooqui · 2017 · Elsevier eBooks
- Perspective, Summary, and Directions for Future Research on Alzheimer’s DiseaseA. A. Farooqui · 2017 · Elsevier eBooks
- Interactions Between Age, Diet, and Insulin and Their Effect on CognitionElisa Félix‐Soriano, María Jesús Moreno-Aliaga, María Javier Ramírez, Maite Solas · 2018 · Elsevier eBooks
- Estudo comparativo da neuroproteção por anticorpos anti-A? contra a toxicidade de oligômeros de A? em cultura diferenciada de neuroblastoma humanoNathalia Reges Pinheiro · 2018 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
- Terapia celular y génica con timulina E IGF-1 en modelos animales de neuroinflamaciónMaría Florencia Zappa Villar · 2018 · El Servicio de Difusión de la Creación Intelectual (National University of La Plata)
- Strategy for Peptide Drug Delivery via Nose-to-Brain Transport Pathways: Challenges to Pharmacotherapy for DementiaNoriyasu Kamei, Mariko Takeda‐Morishita · 2019 · Drug Delivery System
- Effects of anle138b treatment on amyloid-β neurotoxicityCarolina Thomas · 2020 · eDiss (Georg-August-Universität Göttingen)
- Alzheimer-associated Ab oligomers impact the central nervous system to induce peripheral metabolic deregulationJulia Rosauro Clarke, Natalia M. Lyra e Silva, Cláudia Pinto Figueiredo, Rudimar Luiz Frozza, José Henrique Ledo, Danielle Beckman, Carlos K. Katashima, Daniela Soares Razolli, Bruno M. Carvalho, Renata Frazão et al. · 2015 · Americanae (AECID Library)
- Strain-specific profiling of Amyloid-β in Alzheimer´s disease: functional and clinical signatureAneeqa Noor · 2020 · eDiss (Georg-August-Universität Göttingen)
- Faculty Opinions recommendation of Cellular prion protein is essential for oligomeric amyloid-β-induced neuronal cell death.Gerald Werner Zamponi · 2012 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Monomeric ß-Amyloid Interacts with Type-1 Insulin-Like Growth Factor Receptors to Provide Energy Supply to NeuronsMaria Laura Giuffrida, Marianna Flora Tomasello, Giuseppe Pandini, Filippo Caraci, Giuseppe Battaglia, Carla Letizia Busceti, Paola Di Pietro, Giuseppe Pappalardo, Francesco Attanasio, Santina Chiechio et al. · 2020 · Vide Leaf, Hyderabad eBooks
- 嗅神経を介した薬物送達システム英明 志賀, 三輪 高喜 · 2021 · Nihon Bika Gakkai Kaishi (Japanese Journal of Rhinology)
- Caracterização preliminar do isolamento de oligômeros do peptídeo β-amiloide utilizando o anticorpo de cadeia única NUsc1Raquel Maria de Campos · 2018 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
- Diabetes tipo III: mito ou realidade?Jefferson Petto · 2017 · Revista Brasileira de Fisiologia do Exercício
- Insulin and neurodegenerative diseasesHeather Anne Ferris · 2023 · Elsevier eBooks
- Additional file 3 of Prediction of differentially expressed microRNAs in blood as potential biomarkers for Alzheimer’s disease by meta-analysis and adaptive boosting ensemble learningSze Chung Yuen, Xiaonan Liang, Hongmei Zhu, Yongliang Jia, Siu-wai Leung · 2021 · Figshare
- Additional file 2 of Prediction of differentially expressed microRNAs in blood as potential biomarkers for Alzheimer’s disease by meta-analysis and adaptive boosting ensemble learningSze Chung Yuen, Xiaonan Liang, Hongmei Zhu, Yongliang Jia, Siu-wai Leung · 2021 · Figshare
- Additional file 1 of Prediction of differentially expressed microRNAs in blood as potential biomarkers for Alzheimer’s disease by meta-analysis and adaptive boosting ensemble learningSze Chung Yuen, Xiaonan Liang, Hongmei Zhu, Yongliang Jia, Siu-wai Leung · 2021 · Figshare
- Associations between novel anthropometric indices and cognitive function among U.S. older adultsZhichun Tan, Hongmei Deng, Yaxin Nie, Ning Yan, Lixin Ai · 2024 · Research Square
- ACUTE AMYLOID-Β 40 EXPOSURE DISRUPTS METABOLIC INSULIN SIGNALING IN BLOOD-BRAIN BARRIER ENDOTHELIAL CELLSDouglas B. Nelson, Krishna R. Kalari, Karunya K. Kandimalla · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Epidemiology related to confluence of diabetes and AlzheimerPushpa Yadav, Priya Singh · 2025 · Elsevier eBooks
- Altered cell signaling linked to neurodegeneration : Studies on scrapie-infected neuroblastoma cells and activated microgliaC. Svensson · 2011 · DiVA (Stockholm University)
- Additional file 1 of Type 2 diabetes mellitus-associated transcriptome alterations in cortical neurones and associated neurovascular unit cells in the ageing brainJoanna J. Bury, Annabelle Chambers, Paul Roy Heath, Paul G. Ince, Shaw, Pamela J., Fiona Matthews, Carol Brayne, Julie E. Simpson, Stephen B. Wharton · 2021 · Figshare
- Additional file 2 of Type 2 diabetes mellitus-associated transcriptome alterations in cortical neurones and associated neurovascular unit cells in the ageing brainJoanna J. Bury, Annabelle Chambers, Paul Roy Heath, Paul G. Ince, Shaw, Pamela J., Matthews, Fiona E., Carol Brayne, Julie E. Simpson, Stephen B. Wharton · 2021 · Figshare
- Additional file 3 of Type 2 diabetes mellitus-associated transcriptome alterations in cortical neurones and associated neurovascular unit cells in the ageing brainJoanna J. Bury, Annabelle Chambers, Paul Roy Heath, Paul G. Ince, Shaw, Pamela J., Matthews, Fiona E., Carol Brayne, Julie E. Simpson, Stephen B. Wharton · 2021 · Figshare
- Cognitive decline and neurodegenerative risk in diabetes and agingJanvi Sharma, Pooja Devi, Amit Gupta, Chinmoyee Maharana · 2026 · Elsevier eBooks
- Etude préclinique et clinique de la phase précoce de la maladie d'AlzheimerStéphane Epelbaum · 2015 · theses.fr (ABES)
- Caractérisation des mécanismes moléculaires impliqués dans la mise en place des altérations cérébrales dans un modèle préclinique de diabète de type 2Rim Hamzé · 2023 · theses.fr (ABES)
- From molecules to behavior : network effects of Alzheimer's disease-associated amyloid beta peptides in a Drosophila melanogaster larval circuitAnqi Zhou · 2024 · theses.fr (ABES)
- Metabolic dysregulation in Alzheimer’s disease: Mechanisms, markers, and therapeutic prospectsRadhika Mittal, Priya, Jyotirmoy Banerjee, Aparna Dixit · 2026 · International review of neurobiology
- Insulin Action in the BrainHeather A. Ferris · 2026 · Elsevier eBooks
- MiR-7 in neurological disorders: beyond metabolic dysregulationCristina Puigdueta, Virginia Pardo, Marta Torrecilla-Parra, Mario Fernández-de Frutos, José Luis López-Aceituno, Carmen Zamora, Yaiza López-Manchedo, Rebeca Busto, Cristina M. Ramírez · 2026 · Frontiers in Neuroscience
- The interstitial fluid dynamics and diabetes mellitusRukeye Tuerxun, Kaito Takabayashi, Takafumi Kitagawa, Rui Zou, Koyo Mizuta, Koji Kamagata · 2026 · Elsevier eBooks
- Targeting insulin resistance with exercise mimetics: A potential therapeutic strategy for Alzheimer's diseaseHuanhuan Shi, Zhiwei Ke, Bo Wang, Xinan Zhang, Yang Gui, Hu Zhang, Rongxiang Liang · 2026 · Experimental Neurology