The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Oncoplastic Techniques Allow Extensive Resections for Breast-Conserving Therapy of Breast Carcinomas
Open accessAbstract
OBJECTIVE: To assess the oncologic and cosmetic outcomes in women with breast carcinoma who were treated with breast-conserving therapy using oncoplastic techniques with concomitant symmetrization of the contralateral breast. SUMMARY BACKGROUND DATA: Although breast-conserving therapy is the standard form of treatment for invasive breast tumors up to 4 cm, in patients with large, ill-defined, or poorly situated tumors, cosmetic results can be poor and clear resection margins difficult to obtain. The integration of oncoplastic techniques with a concomitant contralateral symmetrization procedure is a novel surgical approach that allows wide excisions and prevents breast deformities. METHODS: This is a prospective study of 101 patients who were operated on for breast carcinoma between July 1985 and June 1999 at the Institut Curie. The procedure was proposed for patients in whom conservative treatment was possible on oncologic grounds but where a standard lumpectomy would have led to poor cosmesis. Standard institutional treatment protocols were followed. All patients received either pre- or postoperative radiotherapy. Seventeen patients received preoperative chemotherapy to downsize their tumors. Mean follow-up was 3.8 years. Results were analyzed statistically using Kaplan-Meier estimates. RESULTS: Mean weight of excised material on the tumor side was 222 g. The actuarial 5-year local recurrence rate was 9.4%, the overall survival rate was 95.7%, and the metastasis-free survival rate was 82.8%. Cosmesis was favorable in 82% of cases. Preoperative radiotherapy resulted in worse cosmesis than when given postoperatively. CONCLUSIONS: The use of oncoplastic techniques and concomitant symmetrization of the contralateral breast allows extensive resections for conservative treatment of breast carcinoma and results in favorable oncologic and esthetic outcomes. This approach might be useful in extending the indications for conservative therapy.
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Primary Chemotherapy To Avoid Mastectomy in Tumors With Diameters of Three Centimeters or More
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Metadata
- Authors
- Clough, K. B., Lewis, J. S., Couturaud, B., Fitoussi, A., Nos, C., & Falcou, M.-C.
- Venue
- Annals of Surgery
- Published
- 2003-01
- Volume
- 237
- Issue
- 1
- Pages
- 26-34
- ISSN
- 0003-4932 (ISSN-L)
- OpenAlex
- W1993707310
- Cited by
- 608
- References
- 12
- FWCI
- 13.16
- Type
- journal article
- Language
- en
- Open access
- green
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- Clough, K. B., Lewis, J. S., Couturaud, B., Fitoussi, A., Nos, C., & Falcou, M.-C. (2003). Oncoplastic Techniques Allow Extensive Resections for Breast-Conserving Therapy of Breast Carcinomas. Annals of Surgery. https://doi.org/10.1097/00000658-200301000-00005
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