Limitations of Sensitivity, Specificity, Likelihood Ratio, and Bayesʼ Theorem in Assessing Diagnostic Probabilities

Moons, Karel G. M.; van Es, Gerrit-Anne; Deckers, Jaap W.; Habbema, J. Dik F.; Grobbee, Diederick E.

doi:10.1097/00001648-199701000-00002

Limitations of Sensitivity, Specificity, Likelihood Ratio, and Bayesʼ Theorem in Assessing Diagnostic Probabilities

We evaluated the extent to which the sensitivity, specificity, and likelihood ratio of the exercise test to diagnose coronary artery disease vary across subgroups of a certain patient population. Among 295 patients suspected of coronary artery disease, as independently determined by coronary angi…