The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.
Acute ingestion of red wine by men activates platelets but does not influence endothelial markers: no effect of white wine
Abstract
Long-term moderate alcohol use is associated with a better cardiovascular risk profile than total abstinence, although the short-term effect of a bolus of alcohol is unclear. The hypothesis tested in this study was that an acute bolus of alcohol would adversely affect the endothelium and platelets. Blood was taken before and 4 h after the ingestion of red or white wine by nine volunteers per group, and by 11 control water-only drinkers at the same time points. Plasma was obtained and markers of platelet activity (beta-thromboglobulin and soluble P selectin) and endothelial cell function (von Willebrand factor and soluble thrombomodulin) measured by enzyme-linked immunosorbent assay. The only marker to change significantly was beta-thromboglobulin, which increased from a median of 10 ng/ml (interquartile range, 8.5-15) before drinking red wine to 16 ng/ml (interquartile range, 14-20) 4 h later (P = 0.0067). We conclude that an acute bolus of red wine, but not white wine, activates platelets but has no substantial effect on the endothelium.
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“TLR-4 knockout mice are protected from insulin resistance induced by lipid infusions (97) .”
From Dietary factors and low-grade inflammation in relation to overweight and obesity (2011) · cites this paper as [97]
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Cited by
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Dietary factors and low-grade inflammation in relation to overweight and obesity
Calder, P. C., Ahluwalia, N., Brouns, F., Buetler, T., Clement, K., Cunningham, K., Esposito, K., Jönsson, L. S., Kolb, H., Lansink, M., et al. (2011) · British Journal of Nutrition · doi:10.1017/s0007114511005460 · Cited by 1,098
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Táborský, M., Ostadal, P., Adam, T., Moravec, O., Gloger, V., Schee, A., & Skála, T. (2017) · Bratislavské lekárske listy/Bratislava medical journal · doi:10.4149/bll_2017_072 · Cited by 25
Táborský, M., Ostadal, P., & Petrek, M. (2012) · Bratislavské lekárske listy/Bratislava medical journal · doi:10.4149/bll_2012_037 · Cited by 10
Grape Wine and Tea Polyphenols in the Modulation of Atherosclerosis and Heart Disease
Omaye, S. T., & Dubick, M. A. (2006) · Modern nutrition · doi:10.1201/9781420006186.ch5 · Cited by 8
Metadata
- Authors
- Blann, A. D., Williams, N. R., Lip, G. Y. H., Rajput-Williams, J., & Howard, A. N.
- Affiliations
- Royal Papworth Hospital (GB)
- Corresponding author
- Blann, A. D.
- Venue
- Blood Coagulation & Fibrinolysis
- Published
- 2002-10
- Volume
- 13
- Issue
- 7
- Pages
- 647-651
- ISSN
- 0957-5235 (ISSN-L)
- OpenAlex
- W2080796783
- Cited by
- 8
- References
- 26
- Citations by year
- 2026: 1 · 2017: 1 · 2015: 1 · 2012: 1
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Blood Coagulation & Fibrinolysis (publishedVersion)
- PubMed (publishedVersion)
- UCL Discovery (University College London) (submittedVersion)
- University of Birmingham Research Portal (University of Birmingham) (submittedVersion)
- Topics
- Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
- Health Sciences › Medicine › Hematology › Platelet Disorders and Treatments
- Health Sciences › Medicine › Hematology › Blood properties and coagulation
- Keywords
- acute alcohol ingestion, red wine, white wine, platelet activation, endothelial function, beta-thromboglobulin, soluble P-selectin, von Willebrand factor, soluble thrombomodulin, cardiovascular risk, moderate drinking
- MeSH terms
- Adult, Aged, Ethanol, beta-Thromboglobulin, Endothelium, Vascular, Enzyme-Linked Immunosorbent Assay, Humans, Male, Middle Aged, Wine, Biomarkers, Platelet Activation
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