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Serial lactate determinations during circulatory shock
Abstract
The time course of lactacidemia was studied prospectively in 17 patients during fluid resuscitation for an episode of noncardiogenic shock, in 5 patients after grand mal seizures, and in 5 patients after successful CPR for cardiac arrest. The 9 patients in whom shock was reversed with fluid administration demonstrated a regular decrease in lactate concentrations, which exceeded 5% of the initial value during the first 60 min of treatment. In the other patients who expired despite similar therapy, lactacidemia was not significantly affected. During circulatory shock, repeated lactate determinations represent a more reliable prognostic index than an initial value taken alone. Changes in lactate concentration can provide an early and objective evaluation of the patient's response to therapy.
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Cited by
Pathogenetic Mechanisms of Septic Shock
Epstein, F. H., & Parrillo, J. E. (1993) · New England Journal of Medicine · doi:10.1056/nejm199305203282008 · Cited by 1,548
Jansen, T. C., van Bommel, J., Schoonderbeek, F. J., Sleeswijk Visser, S. J., van der Klooster, J. M., Lima, A. P., Willemsen, S. P., & Bakker, J. (2010) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200912-1918oc · Cited by 894
Bakker, J., Gris, P., Coffernils, M., Kahn, R. J., & Vincent, J.-L. (1996) · The American Journal of Surgery · doi:10.1016/s0002-9610(97)89552-9 · Cited by 851
Self-citationEffects of perfusion pressure on tissue perfusion in septic shock.
LeDoux, D., Astiz, M. E., Carpati, C. M., & Rackow, E. C. (2000) · Critical Care Medicine · doi:10.1097/00003246-200008000-00007 · Cited by 586
Clinical use of lactate monitoring in critically ill patients
Bakker, J., Nijsten, M. W., & Jansen, T. C. (2013) · Annals of Intensive Care · doi:10.1186/2110-5820-3-12 · Cited by 473
Metadata
- Authors
- VINCENT, J.-L., DUFAYE, P., BERRÉ, J., LEEMAN, M., DEGAUTE, J.-P., & KAHN, R. J.
- Venue
- Critical Care Medicine
- Published
- 1983-06
- Volume
- 11
- Issue
- 6
- Pages
- 449-451
- ISSN
- 0090-3493 (ISSN-L)
- OpenAlex
- W2052756505
- Cited by
- 566
- References
- 0
- FWCI
- 3.88
- Type
- journal article
- Language
- en
- Open access
- closed
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- VINCENT, J.-L., DUFAYE, P., BERRÉ, J., LEEMAN, M., DEGAUTE, J.-P., & KAHN, R. J. (1983). Serial lactate determinations during circulatory shock. Critical Care Medicine. https://doi.org/10.1097/00003246-198306000-00012
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.