Effects of methylphenidate on adolescents with aggressive conduct disorder and ADDH: a preliminary report
Abstract
The effect of methylphenidate on aggression in adolescents diagnosed with both aggressive conduct disorder and attention deficit disorder with hyperactivity was assessed in nine male adolescents. After three open trials, a placebo controlled double-blind design was used. During methylphenidate treatment of the six double-blind subjects, there was a significant reduction of aggressivity (p's less than 0.05), as measured by the Adolescent Antisocial Behavior Checklist. Conners Teacher Rating Scale Hyperactivity and Aggression scores were in the predicted directions, but the differences were not statistically significant.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Initial studies suggest that methylphenidate also has an impact on emotional dysregulation behaviors in ASPD and CD as well as BPD.
“This idea is in line with initial studies, suggesting that methylphenidate also has an impact on emotional dysregulation behaviors in ASPD and CD (Kaplan et al., 1990; Brown et al., 1991; Klein et al., 1997; Connor et al., 2000) as well as BPD (Schulz et al., 1988; Golubchik et al., 2008; Prada et al., 2015; although see Schulz et al. (1988) for possible issue with schizotypal comorbidity).”
From Top-Down Dysregulation—From ADHD to Emotional Instability (2016) · cites this paper as Kaplan et al., 1990
Cited by
Sorted by citations
Methylphenidate for children and adolescents with attention deficit hyperactivity disorder (ADHD)
Storebø, O. J., Ramstad, E., Krogh, H. B., Nilausen, T. D., Skoog, M., Holmskov, M., Rosendal, S., Groth, C., Magnusson, F. L., Moreira-Maia, C. R., et al. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd009885.pub2 · Cited by 347 · see citing works
CONNOR, D. F., GLATT, S. J., LOPEZ, I. D., JACKSON, D., & MELLONI, R. H. (2002) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-200203000-00004 · Cited by 333 · see citing works
Top-Down Dysregulation—From ADHD to Emotional Instability
Petrovic, P., & Castellanos, F. X. (2016) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2016.00070 · Cited by 179 · see citing works
“…ADHD, emotional ADHD and emotional instability disorders such as BPD, ASPD and CD. has an impact on emotional dysregulation behaviors in ASPD and CD (Kaplan et al., 1990; Brown et al., 1991; Klein et al., 1997; Connor et al., 2000) as well as BPD (Schulz et al., 1988; Golubchik et al., 2008;…”
BackgroundVentura, P., de Giambattista, C., Trerotoli, P., Cavone, M., Di Gioia, A., & Margari, L. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11102922 · Cited by 22 · see citing works
- Authors
- KAPLAN, S. L., BUSNER, J., KUPIETZ, S., WASSERMANN, E., & SEGAL, B.
- Affiliations
- Nathan Kline Institute for Psychiatric Research (US)
- Corresponding author
- KAPLAN, STUART L.
- Venue
- Journal of the American Academy of Child & Adolescent Psychiatry
- Publisher
- Elsevier BV
- Published
- 1990-09
- Volume
- 29
- Issue
- 5
- Pages
- 719-723
- ISSN
- 0890-8567 (ISSN-L)
- OpenAlex
- W2055288500
- Cited by
- 99
- References
- 0
- Citations by year
- 2026: 1 · 2025: 1 · 2023: 3 · 2022: 1 · 2021: 2 · 2019: 2 · 2017: 2 · 2016: 3 · 2015: 1 · 2014: 2 · 2012: 1
- FWCI
- 7.61
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of the American Academy of Child & Adolescent Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Keywords
- methylphenidate, attention deficit hyperactivity disorder, aggression, adolescents, stimulant medication, antisocial behavior, hyperactivity
- MeSH terms
- Adolescent, Aggression, Attention Deficit Disorder with Hyperactivity, Double-Blind Method, Humans, Male, Methylphenidate, Social Environment
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
