Cited by 372Anxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesChild and Adolescent Psychosocial and Emotional DevelopmentMaternal Mental Health During Pregnancy and Postpartum

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Predictors of Panic Attacks in Adolescents

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HAYWARD, CHRIS, KILLEN, JOEL D., KRAEMER, HELENA C., TAYLOR, C. BARR·2000·Journal of the American Academy of Child & Adolescent Psychiatry

DOI 10.1097/00004583-200002000-00021

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Abstract

OBJECTIVE: To identify risk factors for onset of panic attacks in adolescents, a prospective cohort design was used to evaluate the following risk factors: negative affectivity, female sex, anxiety sensitivity, and childhood separation anxiety disorder. These risk factors were also evaluated for predicting onset of major depression to test their specificity. METHOD: The sample consisted of 2,365 high school students assessed over a 4-year period. Assessments included self-report questionnaires and structured clinical interviews. Cox proportional hazards models were used to evaluate risk. RESULTS: Consistent with previous studies, prior major depression predicted onset of panic attacks and a history of panic attacks predicted onset of major depression. After adjusting for the effects of prior major depression, negative affectivity and anxiety sensitivity, but not female sex or childhood separation anxiety disorder, predicted onset of 4-symptom panic attacks. However, female sex and negative affectivity but not anxiety sensitivity or childhood separation anxiety disorder predicted onset of major depression after adjustment for the effects of prior panic attacks. CONCLUSION: Negative affectivity appears to be a nonspecific risk factor for panic attacks and major depression, whereas anxiety sensitivity appears to be a specific factor that increases the risk for 4-symptom panic attacks in adolescents.

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Authors: HAYWARD, C., KILLEN, J. D., KRAEMER, H. C., & TAYLOR, C. B.
Affiliations: Stanford Medicine (US)
Corresponding author: HAYWARD, CHRIS
ORCID: KRAEMER, HELENA C.
TAYLOR, C. BARR
Venue: Journal of the American Academy of Child & Adolescent Psychiatry
Publisher: Elsevier BV
Published: 2000-02
Volume: 39
Issue: 2
Pages: 207-214
ISSN: 0890-8567 (ISSN-L)
DOI: 10.1097/00004583-200002000-00021
OpenAlex: W2029700225
Cited by: 371
References: 53
Citations by year: 2026: 2 · 2025: 5 · 2024: 5 · 2023: 9 · 2022: 4 · 2021: 7 · 2020: 8 · 2019: 9 · 2018: 16 · 2017: 7 · 2016: 13 · 2015: 20 · 2014: 22 · 2013: 24 · 2012: 19
FWCI: 12.40
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by-nc-nd
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
creativecommons.org/licenses/by-nc-nd/4.0/ (vor, 3990 d)
Locations: Journal of the American Academy of Child & Adolescent Psychiatry (publishedVersion, cc-by-nc-nd)
PubMed (publishedVersion)
Funders: NIHM (5R01 HD24779-05, 5R01 MH45431-04)
Topics: Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
Keywords: panic attacks, adolescents, risk factors, negative affectivity, anxiety sensitivity, female sex, major depressive disorder, depression onset
MeSH terms: Adolescent, Agoraphobia, Anxiety Disorders, Anxiety, Separation, Child, Major Depressive Disorder, Female, Humans, Male, Personality Inventory, Prospective Studies, Risk Factors, Sex Factors, Panic Disorder

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