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Circadian Rhythm, Sleep, and Epilepsy
Abstract
This review article: (1) describes the circadian distribution of ictal and interictal events; (2) differentiates transitional arousal, non-rapid eye movement and rapid eye movement sleep components and their substrates; (3) suggests the means by which the neural generators of these seizure-prone vs. seizure-resistant sleep and arousal states modulate the timing of different seizure manifestations; (4) considers clinical and mechanistic findings for the reciprocal effects of seizures and antiepileptic drugs upon the sleep-wake cycle; and (5) assesses clinical and basic mechanisms of sleep deprivation effects upon seizures.
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“As reduced sleep is a common parameter in conditions causing mania in patients with bipolar disorder (75) and can also increase the chance of epileptic seizures (76, 77)”
From An Overview of Monthly Rhythms and Clocks (2017) · cites this paper as [77]
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Metadata
- Authors
- Shouse, M. N., Martins da Silva, A., & Sammaritano, M.
- Affiliations
- United States Department of Veterans Affairs (US)
- University of California, Los Angeles (US)
- Corresponding author
- Shouse, Margaret N.
- Venue
- Journal of Clinical Neurophysiology
- Published
- 1996-01
- Volume
- 13
- Issue
- 1
- Pages
- 32-50
- ISSN
- 0736-0258 (ISSN-L)
- OpenAlex
- W1975242759
- Cited by
- 153
- References
- 110
- Citations by year
- 2026: 3 · 2025: 4 · 2024: 1 · 2023: 3 · 2022: 2 · 2021: 3 · 2020: 3 · 2019: 4 · 2018: 1 · 2017: 4 · 2016: 3 · 2015: 6 · 2014: 5 · 2013: 3 · 2012: 3
- FWCI
- 1.80
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Clinical Neurophysiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Clinical Neurology › Epilepsy research and treatment
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
- Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
- Keywords
- circadian rhythm, epilepsy, sleep, seizures, ictal events, REM sleep, NREM sleep, arousal, seizure timing, antiepileptic drugs, sleep-wake cycle, sleep deprivation, seizure susceptibility
- MeSH terms
- Anticonvulsants, Arousal, Brain, Brain Mapping, Circadian Rhythm, Electroencephalography, Epilepsy, Evoked Potentials, Humans, Sleep Deprivation, Sleep Wake Disorders, Sleep, REM
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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