The DOI matches its Crossref record.
Changes in Plasma Norepinephrine to Combat-Related Stimuli among Vietnam Veterans with Posttraumatic Stress Disorder
Abstract
Plasma norepinephrine samples were obtained before and after exposure to auditory stimuli reminiscent of combat from two groups of male Vietnam veterans with combat experience: one with diagnoses of PTSD (N = 15) and one with no mental disorder (N = 6). Results showed a significant 30% rise in plasma norepinephrine for the PTSD group, with no change in the comparison group.
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In the citing paper
“and following exposure to threatening stimuli (Blanchard et al, 1991;Geracioti et al, 2008).”
From Inflammation in Fear- and Anxiety-Based Disorders: PTSD, GAD, and Beyond (2017) · cites this paper as Blanchard et al, 1991
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Biological studies of post-traumatic stress disorder
Pitman, R. K., Rasmusson, A. M., Koenen, K. C., Shin, L. M., Orr, S. P., Gilbertson, M. W., Milad, M. R., & Liberzon, I. (2012) · Nature Reviews Neuroscience · doi:10.1038/nrn3339 · Cited by 1,529
Inflammation in Fear- and Anxiety-Based Disorders: PTSD, GAD, and Beyond
Michopoulos, V., Powers, A., Gillespie, C. F., Ressler, K. J., & Jovanovic, T. (2017) · Neuropsychopharmacology · doi:10.1038/npp.2016.146 · Cited by 786
“Peripheral and central concentrations of norepinephrine are augmented in individuals with PTSD at baseline (Delahanty et al, 2005; Geracioti et al, 2001; Southwick et al, 1999) and following exposure to threatening stimuli (Blanchard et al, 1991; Geracioti et al, 2008).”
BackgroundRole of norepinephrine in the pathophysiology and treatment of posttraumatic stress disorder
Southwick, S. M., Bremner, J. D., Rasmusson, A., Morgan, C. A., Arnsten, A., & Charney, D. S. (1999) · Biological Psychiatry · doi:10.1016/s0006-3223(99)00219-x · Cited by 573
Elzinga, B. (2002) · Journal of Affective Disorders · doi:10.1016/s0165-0327(01)00351-2 · Cited by 473
“Furthermore, plasma noradrenaline was enhanced in veterans with PTSD after exposure to auditory stimuli reminiscent of combat (McFall et al., 1990; Blanchard et al., 1991).”
BackgroundCSF Norepinephrine Concentrations in Posttraumatic Stress Disorder
Geracioti, T. D., Baker, D. G., Ekhator, N. N., West, S. A., Hill, K. K., Bruce, A. B., Schmidt, D., Rounds-Kugler, B., Yehuda, R., Keck, P. E., et al. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.8.1227 · Cited by 462
Metadata
- Authors
- BLANCHARD, E. B., KOLB, L. C., PRINS, A., GATES, S., & McCOY, G. C.
- Affiliations
- State University of New York (US)
- Albany Medical College (US)
- ORCID
- PRINS, ANNABEL
- Venue
- The Journal of Nervous and Mental Disease
- Published
- 1991-06
- Volume
- 179
- Issue
- 6
- Pages
- 371-373
- ISSN
- 0022-3018 (ISSN-L)
- OpenAlex
- W1964972447
- Cited by
- 152
- References
- 0
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 2 · 2023: 4 · 2022: 1 · 2021: 3 · 2020: 5 · 2019: 3 · 2018: 2 · 2017: 6 · 2016: 10 · 2015: 4 · 2014: 6 · 2013: 2 · 2012: 3
- FWCI
- 4.83
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Nervous and Mental Disease (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Mental Health (MH-37838)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Health Sciences › Medicine › Clinical Neurology › Traumatic Brain Injury Research
- Keywords
- plasma norepinephrine, post-traumatic stress disorder, Vietnam War veterans, autonomic arousal, combat exposure
- MeSH terms
- Acoustic Stimulation, Adult, Diagnosis, Differential, Humans, Male, Memory, Norepinephrine, Posture, Stress Disorders, Post-Traumatic, Tape Recording, Veterans, Vietnam, Warfare
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