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Behavior of Mild Cervical Dysplasia During Long-Term Follow-up
Abstract
Five hundred and fifty-five women with cervical cytologically diagnosed mild cervical dysplasia were followed by cytology without major treatment. Biopsies were performed in 14% resulting in no significant influence on the outcome of the studied material. Regression to normal occurred in 62% (follow-up 39 months), progression to severe dysplasia/carcinoma in situ/invasive carcinoma in 16% (invasive carcinoma: two patients), and persistence of dysplasia in 22%. Life table analysis calculated the risk of progression of mild dysplasia to be 250 to 800/100,000 women/year. A comparison with the incidence of carcinoma in situ, four of 100,000 women/year, illustrates the yearly risk for a woman with mild dysplasia as 560 times greater than for a woman without cervical dysplasia to develop severe dysplasia/carcinoma in situ/invasive carcinoma.(Obstet Gynecol 67:665, 1986)
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Cited by
Natural History of Cervicovaginal Papillomavirus Infection in Young Women
Ho, G. Y. F., Bierman, R., Beardsley, L., Chang, C. J., & Burk, R. D. (1998) · New England Journal of Medicine · doi:10.1056/nejm199802123380703 · Cited by 2,329
Human Papillomavirus Testing in the Prevention of Cervical Cancer
Schiffman, M., Wentzensen, N., Wacholder, S., Kinney, W., Gage, J. C., & Castle, P. E. (2011) · JNCI: Journal of the National Cancer Institute · doi:10.1093/jnci/djq562 · Cited by 759
Natural History of Dysplasia of the Uterine Cervix
Holowaty, P., Miller, A. B., Rohan, T., & To, T. (1999) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/91.3.252 · Cited by 608
Regression of low-grade squamous intra-epithelial lesions in young women
Moscicki, A.-B., Shiboski, S., Hills, N. K., Powell, K. J., Jay, N., Hanson, E. N., Miller, S., Canjura-Clayton, L. K., Farhat, S., Broering, J. M., et al. (2004) · The Lancet · doi:10.1016/s0140-6736(04)17354-6 · Cited by 448
Cannistra, S. A., & Niloff, J. M. (1996) · New England Journal of Medicine · doi:10.1056/nejm199604183341606 · Cited by 365
Metadata
- Authors
- NASIELL, K., ROGER, V., & NASIELL, M.
- Venue
- Obstetrics & Gynecology
- Published
- 1986-05
- Volume
- 67
- Issue
- 5
- Pages
- 665-669
- ISSN
- 0029-7844 (ISSN-L)
- OpenAlex
- W4251542078
- Cited by
- 294
- References
- 0
- FWCI
- 3.06
- Type
- journal article
- Language
- en
- Open access
- closed
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- NASIELL, K., ROGER, V., & NASIELL, M. (1986). Behavior of Mild Cervical Dysplasia During Long-Term Follow-up. Obstetrics & Gynecology. https://doi.org/10.1097/00006250-198605000-00012
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
