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Children hospitalized with influenza B infection
Abstract
An outbreak of influenza virus type B infection occurred in Philadelphia from December, 1985, to April, 1986. During this epidemic 24 patients were admitted to Children's Hospital from whom influenza B was isolated from routine respiratory viral cultures. All were younger than 3 years of age. Clinical findings included fever (greater than or equal to 38 degrees C) (88%), rhinorrhea (62.6%), cough (50%), otitis (50%), rhonchi (42%), vomiting (38%), diarrhea (33%), rales (21%), pharyngitis (13%) and croup (4%). Remarkably 75% of the patients had underlying diseases which may have contributed to the severity of the infection. Nine (41%) patients had pneumonia. Two patients died of respiratory failure caused by overwhelming influenza B virus infection. Patients admitted to the hospital with respiratory and underlying diseases should have viral respiratory cultures which include influenza B.
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Our findings and others indicate that fatal disease in children can occur in the absence of concomitant bacterial pneumonia.
“Nonetheless, our findings and others [24,34] indicate that fatal disease in children can occur in the absence of concomitant bacterial pneumonia.”
From Myocardial Injury and Bacterial Pneumonia Contribute to the Pathogenesis of Fatal Influenza B Virus Infection (2012) · cites this paper as [24]
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Metadata
- Authors
- LIOU, Y.-S., BARBOUR, S. D., BELL, L. M., & PLOTKIN, S. A.
- Affiliations
- Children's Hospital of Philadelphia (US)
- Corresponding author
- LIOU, YI-SHENG
- Venue
- The Pediatric Infectious Disease Journal
- Published
- 1987-06
- Volume
- 6
- Issue
- 6
- Pages
- 541-543
- ISSN
- 0891-3668 (ISSN-L)
- OpenAlex
- W2064229264
- Cited by
- 39
- References
- 0
- Citations by year
- 2022: 1 · 2021: 1 · 2019: 1 · 2017: 1 · 2013: 1 · 2012: 3
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Pediatric Infectious Disease Journal (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Influenza Virus Research Studies
- Health Sciences › Medicine › Epidemiology › Respiratory viral infections research
- Health Sciences › Medicine › Epidemiology › Pneumonia and Respiratory Infections
- Keywords
- influenza B, pediatric influenza, influenza outbreak, hospitalized children, pneumonia, underlying chronic disease, respiratory failure
- MeSH terms
- Child, Preschool, Disease Outbreaks, Female, Humans, Infant, Infant, Newborn, Influenza, Human, Inpatients, Male, Influenza B virus, Pennsylvania, Retrospective Studies
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