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Cited by 407Musculoskeletal pain and rehabilitationPain Management and Placebo EffectAcupuncture Treatment Research Studies

The DOI matches its Crossref record, with a small difference in title or year; 35 of the 35 references it cites were found in a registry or an index.

Lessons from a Trial of Acupuncture and Massage for Low Back Pain: Patient Expectations and Treatment Effects

Kalauokalani, Donna, Cherkin, Daniel C., Sherman, Karen J., Koepsell, Thomas D., Deyo, Richard A.·2001·Spine
DOI 10.1097/00007632-200107010-00005
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Abstract

STUDY DESIGN: A subanalysis of data derived from a randomized clinical trial was performed. OBJECTIVE: To evaluate the association of a patient's expectation for benefit from a specific treatment with improved functional outcome. SUMMARY OF BACKGROUND DATA: Psychosocial factors, ambiguous diagnoses, and lack of a clearly superior treatment have complicated the management of patients with chronic low back pain. The authors hypothesized that patient expectation for benefit from a specific treatment is associated with improved functional outcomes when that treatment is administered. METHODS: In a randomized trial, 135 patients with chronic low back pain who received acupuncture or massage were studied. Before randomization, study participants were asked to describe their expectations regarding the helpfulness of each treatment on a scale of 0 to 10. The primary outcome was level of function at 10 weeks as measured by the modified Roland Disability scale. RESULTS: After adjustment for baseline characteristics, improved function was observed for 86% of the participants with higher expectations for the treatment they received, as compared with 68% of those with lower expectations (P = 0.01). Furthermore, patients who expected greater benefit from massage than from acupuncture were more likely to experience better outcomes with massage than with acupuncture, and vice versa (P = 0.03). CONCLUSIONS: The results of this study suggest that patient expectations may influence clinical outcome independently of the treatment itself. In contrast, general optimism about treatment, divorced from a specific treatment, is not strongly associated with outcome. These results may have important implications for clinical trial design and recruitment, and may help to explain the apparent success of some conventional and alternative therapies in trials that do not control for patient expectations. The findings also may be important for therapy choices made in the clinical setting.

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Crossref · 10.1097/00007632-200107010-00005

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35 of 35 references verified0 citation errors · 0 not checkable

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Research works printed but not linked: 1

  1. Woolley, 1978, Soc Sci Med, 12, 123

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Metadata

Authors
Kalauokalani, D., Cherkin, D. C., Sherman, K. J., Koepsell, T. D., & Deyo, R. A.
Affiliations
  • Washington University in St. Louis (US)
  • Group Health Cooperative (US)
  • University of Washington (US)
Corresponding author
Kalauokalani, Donna
ORCID
Venue
Spine
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2001-07
Volume
26
Issue
13
Pages
1418-1424
ISSN
0362-2436 (ISSN-L)
DOI
10.1097/00007632-200107010-00005
OpenAlex
W2070426225
Cited by
407
References
35
Citations by year
2026: 4 · 2025: 6 · 2024: 3 · 2023: 9 · 2022: 14 · 2021: 13 · 2020: 15 · 2019: 12 · 2018: 9 · 2017: 15 · 2016: 24 · 2015: 15 · 2014: 14 · 2013: 23 · 2012: 20
FWCI
10.69
Type
journal article
Language
en
Open access
closed
Locations
  • Spine (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Dartmouth-Hitchcock Medical Center
  • Agency for Healthcare Research and Quality (HS 09351)
Topics
  • Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Musculoskeletal pain and rehabilitation
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Pain Management and Placebo Effect
  • Health Sciences › Medicine › Complementary and alternative medicine › Acupuncture Treatment Research Studies
Keywords
chronic low back pain, acupuncture, massage, patient expectations, treatment expectations, functional outcome, placebo effect, psychosocial factors, clinical trial design, trial recruitment
MeSH terms
Adult, Aged, Female, Humans, Male, Massage, Middle Aged, Acupuncture Therapy, Treatment Outcome, Patient Satisfaction, Low Back Pain

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