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The Malmö diet and cancer study: representativity, cancer incidence and mortality in participants and non-participants
Abstract
In order to investigate potential selection bias in population-based cohort studies, participants (n = 28098) and non-participants (n = 40807) in the Malmö Diet and Cancer Study (MDCS) were compared with regard to cancer incidence and mortality. MDCS participants were also compared with participants in a mailed health survey with regard to subjective health, socio-demographic characteristics and lifestyle. Cancer incidence prior to recruitment was lower in non-participants, Cox proportional hazards analysis yielded a relative risk (RR) with a 95% confidence interval of 0.95 (0.90-1.00), compared with participants. During recruitment, cancer incidence was higher in non-participants, RR: 1.08 (1.01-1.17). Mortality was higher in non-participants both during, 3.55 (3.13-4.03), and following the recruitment period, 2.21 (2.03-2.41). The proportion reporting good health was higher in the MDCS than in the mailed health survey (where 74.6% participated), but the socio-demographic structure was similar. We conclude that mortality is higher in non-participants than in participants during recruitment and follow-up. It is also suggested that non-participants may have a lower cancer incidence prior to recruitment but a higher incidence during the recruitment period.
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Metadata
- Authors
- Manjer, J., Carlsson, S., Elmståhl, S., Gullberg, B., Janzon, L., Lindström, M., Mattisson, I., & Berglund, G.
- Venue
- European Journal of Cancer Prevention
- Published
- 2001-12
- Volume
- 10
- Issue
- 6
- Pages
- 489-499
- ISSN
- 0959-8278 (ISSN-L)
- OpenAlex
- W2002348222
- Cited by
- 542
- References
- 0
- FWCI
- 2.31
- Type
- journal article
- Language
- en
- Open access
- closed
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- Manjer, J., Carlsson, S., Elmståhl, S., Gullberg, B., Janzon, L., Lindström, M., Mattisson, I., & Berglund, G. (2001). The Malmö diet and cancer study: representativity, cancer incidence and mortality in participants and non-participants. European Journal of Cancer Prevention. https://doi.org/10.1097/00008469-200112000-00003
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