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Cited by 435

The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.

Prevalence of Asymptomatic Carotid Artery Stenosis in the General Population: An Individual Participant Data Meta-Analysis

Open access
de Weerd, Marjolein, Greving, Jacoba P., Hedblad, Bo, Lorenz, Matthias W., Mathiesen, Ellisiv B., O'Leary, Daniel H., Rosvall, Maria, Sitzer, Matthias, Buskens, Erik, Bots, Michiel L.·2010·Stroke
DOI 10.1161/strokeaha.110.581058
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Abstract

Background and Purpose— In the discussion on the cost-effectiveness of screening, precise estimates of severe asymptomatic carotid stenosis are vital. Accordingly, we assessed the prevalence of moderate and severe asymptomatic carotid stenosis by age and sex using pooled cohort data. Methods— We performed an individual participant data meta-analysis (23 706 participants) of 4 population-based studies (Malmö Diet and Cancer Study, Tromsø, Carotid Atherosclerosis Progression Study, and Cardiovascular Health Study). Outcomes of interest were asymptomatic moderate (≥50%) and severe carotid stenosis (≥70%). Results— Prevalence of moderate asymptomatic carotid stenosis ranged from 0.2% (95% CI, 0.0% to 0.4%) in men aged <50 years to 7.5% (5.2% to 10.5%) in men aged ≥80 years. For women, this prevalence increased from 0% (0% to 0.2%) to 5.0% (3.1% to 7.5%). Prevalence of severe asymptomatic carotid stenosis ranged from 0.1% (0.0% to 0.3%) in men aged <50 years to 3.1% (1.7% to 5.3%) in men aged ≥80. For women, this prevalence increased from 0% (0.0% to 0.2%) to 0.9% (0.3% to 2.4%). Conclusions— The prevalence of severe asymptomatic carotid stenosis in the general population ranges from 0% to 3.1%, which is useful information in the discussion on the cost-effectiveness of screening.

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Metadata

Authors
de Weerd, M., Greving, J. P., Hedblad, B., Lorenz, M. W., Mathiesen, E. B., O'Leary, D. H., Rosvall, M., Sitzer, M., Buskens, E., & Bots, M. L.
Venue
Stroke
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2010-06
Volume
41
Issue
6
Pages
1294-1297
ISSN
  • 0039-2499 (ISSN-L)
  • 1524-4628
DOI
10.1161/strokeaha.110.581058
OpenAlex
W2154532030
Cited by
435
References
32
FWCI
15.25
Type
journal article
Language
en
Open access
bronze

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de Weerd, M., Greving, J. P., Hedblad, B., Lorenz, M. W., Mathiesen, E. B., O'Leary, D. H., Rosvall, M., Sitzer, M., Buskens, E., & Bots, M. L. (2010). Prevalence of Asymptomatic Carotid Artery Stenosis in the General Population: An Individual Participant Data Meta-Analysis. Stroke. https://doi.org/10.1161/strokeaha.110.581058

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.