Cited by 299Musculoskeletal pain and rehabilitationMyofascial pain diagnosis and treatmentTemporomandibular Joint Disorders

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A Cochrane Review of Manipulation and Mobilization for Mechanical Neck Disorders

Gross, Anita R., Hoving, Jan L., Haines, Ted A., Goldsmith, Charles H., Kay, T, Aker, Peter, Bronfort, Gert·2004·Spine

DOI 10.1097/01.brs.0000131218.35875.ed

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Abstract

Study design and objectives Our systematic review of randomized trials assessed whether manipulation and mobilization relieve pain or improve function/disability, patient satisfaction, and global perceived effect in adults with mechanical neck disorders. Summary of background data Neck disorders are common, disabling, and costly. Methods Computerized bibliographic databases were searched up to March 2002. Two independent reviewers conducted study selection, data abstraction, and methodologic quality assessment. Relative risk and standardized mean differences were calculated. In the absence of heterogeneity, pooled effect measures were calculated using a random effects model. Results Of the 33 selected trials, 42% were high quality trials. Single or multiple (3-11) sessions of manipulation or mobilization showed no benefit in pain relief when assessed against placebo, control groups, or other treatments for acute/subacute/chronic mechanical neck disorders with or without headache. There was strong evidence of benefit favoring multimodal care (mobilization and/or manipulation plus exercise) over a waiting list control for pain reduction [pooled standardized mean differences -0.85 (95% CI: -1.20 to -0.50)], improvement in function [pooled SMD -0.57 (95% CI: -0.94 to -0.21)] and global perceived effect [standardized mean differences -2.73 (95% CI: -3.30 to -2.16)] for subacute/chronic mechanical neck disorders with or without headache. Conclusions Mobilization and/or manipulation…

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Authors: Gross, A. R., Hoving, J. L., Haines, T. A., Goldsmith, C. H., Kay, T., Aker, P., & Bronfort, G.
Affiliations: McMaster University (CA)
Monash University (AU)
Northwestern Health Sciences University (US)
University of Toronto (CA)
Canadian Memorial Chiropractic College (CA)
Corresponding author: Gross, Anita R.
Haines, Ted A.
Goldsmith, Charles H.
ORCID: Gross, Anita R.
Hoving, Jan L.
Venue: Spine
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2004-07
Volume: 29
Issue: 14
Pages: 1541-1548
ISSN: 0362-2436 (ISSN-L)
DOI: 10.1097/01.brs.0000131218.35875.ed
OpenAlex: W2016127346
Cited by: 299
References: 80
Citations by year: 2026: 3 · 2025: 3 · 2024: 2 · 2023: 5 · 2022: 10 · 2021: 7 · 2020: 6 · 2019: 6 · 2018: 10 · 2017: 14 · 2016: 11 · 2015: 16 · 2014: 17 · 2013: 15 · 2012: 16
FWCI: 2.15
Type: journal article
Language: en
Open access: closed
Locations: Spine (publishedVersion)
PubMed (publishedVersion)
Data Archiving and Networked Services (DANS) (submittedVersion)
Pure Amsterdam UMC (submittedVersion)
Funders: National Center for Complementary and Integrative Health (U01AT000170, AT 00170-05)
Topics: Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Musculoskeletal pain and rehabilitation
Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Myofascial pain diagnosis and treatment
Health Sciences › Dentistry › Oral Surgery › Temporomandibular Joint Disorders
Keywords: spinal manipulation, spinal mobilization, neck pain, headache, exercise therapy, multimodal care, neck function, treatment effectiveness
MeSH terms: Adult, Aged, Combined Modality Therapy, Exercise Therapy, Female, Headache, Humans, Male, Middle Aged, Pain Measurement, Randomized Controlled Trials as Topic, Treatment Outcome, Patient Satisfaction, Evidence-Based Medicine, Neck Pain, Recovery of Function, Manipulation, Spinal, Physical Therapy Modalities, Manipulation, Chiropractic

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A Cochrane Review of Manipulation and Mobilization for Mechanical Neck Disorders

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