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Cited by 335

The DOI matches its Crossref record; 79 of the 79 references it cites were found in a registry or an index.

Induced hypothermia in critical care medicine: A review

Bernard, Stephen A., Buist, Michael·2003·Critical Care Medicine

Abstract

BACKGROUND: Clinical trials of induced hypothermia have suggested that this treatment may be beneficial in selected patients with neurologic injury. OBJECTIVES: To review the topic of induced hypothermia as a treatment of patients with neurologic and other disorders. DESIGN: Review article. INTERVENTIONS: None. MAIN RESULTS: Improved outcome was demonstrated in two prospective, randomized, controlled trials in which induced hypothermia (33 degrees C for 12-24 hrs) was used in patients with anoxic brain injury following resuscitation from prehospital cardiac arrest. In addition, prospective, randomized, controlled trials have been conducted in patients with severe head injury, with variable results. There also have been preliminary clinical studies of induced hypothermia in patients with severe stroke, newborn hypoxic-ischemic encephalopathy, neurologic infection, and hepatic encephalopathy, with promising results. Finally, animal models have suggested that hypothermia that is induced rapidly following traumatic cardiac arrest provides significant neurologic protection and improved survival. CONCLUSIONS: Induced hypothermia has a role in selected patients in the intensive care unit. Critical care physicians should be familiar with the physiologic effects, current indications, techniques, and complications of induced hyperthermia.

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Metadata

Authors
Bernard, S. A., & Buist, M.
Venue
Critical Care Medicine
Published
2003-07
Volume
31
Issue
7
Pages
2041-2051
ISSN
0090-3493 (ISSN-L)
OpenAlex
W2008653692
Cited by
335
References
79
FWCI
20.27
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Induced hypothermia in critical care medicine: A review. https://app.cochat.ai/papers/10.1097/01.ccm.0000069731.18472.61
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Bernard, S. A., & Buist, M. (2003). Induced hypothermia in critical care medicine: A review. Critical Care Medicine. https://doi.org/10.1097/01.ccm.0000069731.18472.61

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.