The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.
Sepsis incidence and outcome: Contrasting the intensive care unit with the hospital ward*
Abstract
OBJECTIVE: To describe the outcome of patients with sepsis according to location on a ward or in an intensive care unit. DESIGN: Prospective multicentered observational study. SETTING: Three academic hospitals in Madrid, Spain. PATIENTS: Consecutive patients with sepsis admitted to participating hospitals from March 1 to June 30, 2003. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: During the study period, 15,852 patients >18 yrs of age were admitted. Sepsis was identified in 702 patients, giving an estimated cumulative incidence rate of 367 cases per 100,000 adult area residents per year and a cumulative incidence rate among patients admitted to the hospital of 4.4%. Most septic patients had a community-acquired infection (71%). Severe sepsis developed in 199 patients (incidence rate, 104 cases per 100,000 adult area residents per year), and 59 patients developed septic shock (incidence rate, 31 cases per 100,000 adult area residents per year). Most of the patients met the criteria for severe sepsis or septic shock on the same day that they would have qualified for the septic status one step down the scale. In the other patients, the median time between sepsis and severe sepsis was 2 days (interquartile range, 2-5) and between severe sepsis and septic shock was 3 days (interquartile range, 1-4). Only 32% of severe sepsis patients received intensive care. The hospital mortality for all septic patients was 12.8%; for severe sepsis, 20.7%; and for septic shock, 45.7%. CONCLUSIONS: This study shows the high incidence of sepsis in a general population of patients admitted to hospital. A significant proportion of patients with severe sepsis are not transferred to the intensive care unit.
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Cites
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Martin, G. S., Mannino, D. M., Eaton, S., & Moss, M. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa022139 · Cited by 5,841
2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference
Conference, F. T. I. S. D., Levy, M. M., Fink, M. P., Marshall, J. C., Abraham, E., Angus, D., Cook, D., Cohen, J., Opal, S. M., Vincent, J.-L., et al. (2003) · Intensive Care Medicine · doi:10.1007/s00134-003-1662-x · Cited by 2,871
Sepsis in European intensive care units: Results of the SOAP study*
Vincent, J.-L., Sakr, Y., Sprung, C. L., Ranieri, V. M., Reinhart, K., Gerlach, H., Moreno, R., Carlet, J., Le Gall, J.-R., & Payen, D. (2006) · Critical Care Medicine · doi:10.1097/01.ccm.0000194725.48928.3a · Cited by 2,836
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Cited by
Fleischmann, C., Scherag, A., Adhikari, N. K. J., Hartog, C. S., Tsaganos, T., Schlattmann, P., Angus, D. C., & Reinhart, K. (2016) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201504-0781oc · Cited by 3,548
Mayr, F. B., Yende, S., & Angus, D. C. (2014) · Virulence · doi:10.4161/viru.27372 · Cited by 1,208
Ferrer, R. (2008) · JAMA · doi:10.1001/jama.299.19.2294 · Cited by 741
Sartelli, M., Chichom-Mefire, A., Labricciosa, F. M., Hardcastle, T., Abu-Zidan, F. M., Adesunkanmi, A. K., Ansaloni, L., Bala, M., Balogh, Z. J., Beltrán, M. A., et al. (2017) · World Journal of Emergency Surgery · doi:10.1186/s13017-017-0141-6 · Cited by 494
Effectiveness of treatments for severe sepsis: A prospective, multicenter, observational study.
Ferrer, R., Artigas, A., Suarez, D., Palencia, E., Levy, M. M., Arenzana, A., Pérez, X. L., & Sirvent, J.-M. (2009) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200812-1912oc · Cited by 433
Metadata
- Authors
- Esteban, A., Frutos-Vivar, F., Ferguson, N. D., Peñuelas, O., Lorente, J. Á., Gordo, F., Honrubia, T., Algora, A., Bustos, A., García, G., Diaz-Regañón, I. R., & de Luna, R. R.
- Venue
- Critical Care Medicine
- Published
- 2007-05
- Volume
- 35
- Issue
- 5
- Pages
- 1284-1289
- ISSN
- 0090-3493 (ISSN-L)
- OpenAlex
- W1993440563
- Cited by
- 372
- References
- 29
- FWCI
- 7.33
- Type
- journal article
- Language
- en
- Open access
- closed
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- Esteban, A., Frutos-Vivar, F., Ferguson, N. D., Peñuelas, O., Lorente, J. Á., Gordo, F., Honrubia, T., Algora, A., Bustos, A., García, G., Diaz-Regañón, I. R., & de Luna, R. R. (2007). Sepsis incidence and outcome: Contrasting the intensive care unit with the hospital ward*. Critical Care Medicine. https://doi.org/10.1097/01.ccm.0000260960.94300.de
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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