The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Disseminated intravascular coagulation
Abstract
OBJECTIVE: To review the current knowledge on the clinical manifestation, pathogenesis, diagnosis, and management of disseminated intravascular coagulation (DIC). DATA SOURCE: Selected articles from the MEDLINE database. DATA SYNTHESIS: DIC may complicate a variety of disorders and can cause significant morbidity (in particular related to organ dysfunction and bleeding) and may contribute to mortality. The pathogenesis of DIC is based on tissue factor-mediated initiation of systemic coagulation activation that is insufficiently contained by physiologic anticoagulant pathways and amplified by impaired endogenous fibrinolysis. The diagnosis of DIC can be made using routinely available laboratory tests and scoring algorithms. Supportive treatment of DIC may be aimed at replacement of platelets and coagulation factors, anticoagulant treatment, and restoration of anticoagulant pathways. CONCLUSIONS: Insight into the pathogenesis of DIC has resulted in better strategies for clinical management, including straightforward diagnostic criteria and potentially beneficial supportive treatment options.
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Citations
Cites
Taylor, F., Toh, C.-H., Hoots, K., Wada, H., & Levi, M. (2001) · Thrombosis and Haemostasis · doi:10.1055/s-0037-1616068 · Cited by 2,285
Self-citationTreating Patients with Severe Sepsis
Wheeler, A. P., & Bernard, G. R. (1999) · New England Journal of Medicine · doi:10.1056/nejm199901213400307 · Cited by 992
Tissue factor in infection and severe inflammation
Levi, M., van der Poll, T., & ten Cate, H. (2006) · Seminars in Thrombosis and Hemostasis · doi:10.1055/s-2006-933338 · Cited by 126
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Cited by
Erez, O., Mastrolia, S. A., & Thachil, J. (2015) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2015.03.054 · Cited by 170
Erez, O., Novack, L., Beer-Weisel, R., Dukler, D., Press, F., Zlotnik, A., Than, N. G., Tomer, A., & Mazor, M. (2014) · PLoS ONE · doi:10.1371/journal.pone.0093240 · Cited by 146
DIC: which laboratory tests are most useful
Levi, M., & Meijers, J. C. (2011) · Blood Reviews · doi:10.1016/j.blre.2010.09.002 · Cited by 146
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Metadata
- Authors
- Levi, M.
- Venue
- Critical Care Medicine
- Published
- 2007-09
- Volume
- 35
- Issue
- 9
- Pages
- 2191-2195
- ISSN
- 0090-3493 (ISSN-L)
- OpenAlex
- W1967499351
- Cited by
- 324
- References
- 3
- FWCI
- 14.19
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
