The DOI matches its Crossref record; 65 of the 65 references it cites were found in a registry or an index.
The ???small for size??? liver syndrome
Abstract
Purpose of review Small-for-size syndrome (SFSS) is a clinical syndrome described following liver transplantation (LT) and extended hepatectomy. New evidence has emerged documenting the importance of preoperative evaluation of functional liver mass, liver quality, influence of portal hypertension, and variations in surgical technique to improve outcome. Recent findings SFSS is characterized by postoperative coagulopathy and liver dysfunction due to insufficient functional liver mass. Recent radiologic advances allow accurate preoperative estimation of total, graft, and remnant liver volume (RLV). In adult-to-adult living donor liver transplantation (LDLT), a graft-to-recipient body weight ratio > or = 0.8% or graft weight ratio > or = 30% are important to avoid SFSS. Minimal functional RLV following extended hepatectomy is > or = 25% in a normal liver, and > or = 40% with preoperative liver dysfunction. Preoperative portal vein or hepatic artery embolization to increase RLV and function after extended hepatectomy, and the increasing use of parenchymal-sparing segmental resections have improved outcome. In LT, the evolving use of split livers, LDLT and marginal grafts has resulted in increased recognition of SFSS. This has led to a renewed interest in defining the pathophysiology, and the development of new surgical techniques to reduce its incidence. Summary Current radiologic imaging techniques can be used to evaluate liver volume and the risk of SFSS following LT and extend…
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“SFSS is associated with a liver remnant or graft to body weight ratio <0.8% or a remnant to total liver volume of less than 25%–30%, where the liver is too small to handle post-operative metabolic demands.157”
From Distinct hepatocyte identities in liver homeostasis and regeneration (2023) · cites this paper as [157]
In the citing paper
“In addition to loss of zonal hepatocyte identity and hepatocyte cell death associated with acute liver failure or chronic liver disease, insufficient functional hepatic mass either following hepatic transplantation or after resection, termed small-for-size syndrome (SFSS), can be fatal.”
From Distinct hepatocyte identities in liver homeostasis and regeneration (2023) · cites this paper as [157]
Citations
Cites
Jarnagin, W. R., Gönen, M., Fong, Y., DeMatteo, R. P., Ben‐Porat, L., Little, S., Corvera, C. U., Weber, S., & Blumgart, L. H. (2002) · PubMed Central · doi:10.1097/01.sla.0000029003.66466.b3 · Cited by 1,476
Improvement in Perioperative Outcome After Hepatic Resection
Jarnagin, W. R., Gönen, M., Fong, Y., DeMatteo, R. P., Ben‐Porat, L., Little, S., Corvera, C. U., Weber, S., & Blumgart, L. H. (2002) · Annals of Surgery · doi:10.1097/00000658-200210000-00001 · Cited by 1,259
Calculation of child and adult standard liver volume for liver transplantation
Urata, K., Kawasaki, S., Matsunami, H., Hashikura, Y., Ikegami, T., Ishizone, S., 百瀬, 芳., Komiyama, A., & Makuuchi, M. (1995) · Hepatology · doi:10.1002/hep.1840210515 · Cited by 984
IMPACT OF GRAFT SIZE MISMATCHING ON GRAFT PROGNOSIS IN LIVER TRANSPLANTATION FROM LIVING DONORS1,2
Kiuchi, T., Kasahara, M., Uryuhara, K., Inomata, Y., Üemoto, S., Asonuma, K., Egawa, H., Fujita, S., Hayashi, M., & Tanaka, K. (1999) · Transplantation · doi:10.1097/00007890-199901270-00024 · Cited by 962
Kubota, K., Makuuchi, M., Kusaka, K., Kobayashi, T., Miki, K., Hasegawa, K., Harihara, Y., & Takayama, T. (1997) · Hepatology · doi:10.1002/hep.510260514 · Cited by 736
Vauthey, J., Chaoui, A. S., Do, K.-A., Bilimoria, M. M., Fenstermacher, M. J., Charnsangavej, C., Hicks, M. E., Alsfasser, G., Lauwers, G. Y., Hawkins, I. F., et al. (2000) · Surgery · doi:10.1067/msy.2000.105294 · Cited by 700
Body surface area and body weight predict total liver volume in Western adults
Vauthey, J., Abdalla, E. K., Doherty, D. A., Gertsch, P., Fenstermacher, M. J., Loyer, E. M., Lerut, J., Materne, R., Wang, X., Encarnacion, A., et al. (2002) · Liver Transplantation · doi:10.1053/jlts.2002.31654 · Cited by 637
Adult-to-Adult Living Donor Liver Transplantation Using Extended Right Lobe Grafts
Lo, C., Fan, S.-T., Liu, C., Wei, W., Lo, R. J. W., Lai, C., Chan, J. K. F., Ng, I. O., Fung, A. S. M., & Wong, J. (1997) · Annals of Surgery · doi:10.1097/00000658-199709000-00005 · Cited by 578
Kurihara, T., Itoi, T., Sofuni, A., Itokawa, F., Tsuchiya, T., Ishii, K., Tsuji, S., Ikeuchi, N., & Moriyasu, F. (2011) · Hepatogastroenterology · doi:10.5754/hge11764 · Cited by 557
Azoulay, D., Castaing, D., Smail, A., Adam, R. A., Cailliez, V., Laurent, A., Lemoine, A., & Bismuth, H. (2000) · Annals of Surgery · doi:10.1097/00000658-200004000-00005 · Cited by 538
Research works printed but not linked: 10
- Kubota, 1997, Hepatology, 26, 1176
- Lin, 1998, Hepatogastroenterology, 45, 1069
- Bennink, 2004, J Nucl Med, 45, 965
- Takeuchi, 1997, Hepatology, 26, 1092
- Hemming, 2003, Ann Surg, 237, 686
- Hirohashi, 2004, Hepatogastroenterology, 51, 1084
- Kubo, 2002, J Surg Res, 107, 113, 10.1016/S0022-4804(02)96503-0 · DOI
- Gertsch, 1997, Eur J Surg, 163, 297
- Man, 2003, Ann Surg, 237, 256
- Sato, 2002, Hepatogastroenterology, 49, 1652
Cited by
Sorted by citations
Schnitzbauer, A. A., Lang, S. A., Goessmann, H., Nadalin, S., Baumgart, J., Farkas, S. A., Fichtner‐Feigl, S., Lorf, T., Goralcyk, A., Hörbelt, R., et al. (2012) · Annals of Surgery · doi:10.1097/sla.0b013e31824856f5 · Cited by 1,330
Regulation of hepatic blood flow: The hepatic arterial buffer response revisited
Eipel, C. (2010) · World Journal of Gastroenterology · doi:10.3748/wjg.v16.i48.6046 · Cited by 557
How Much Remnant Is Enough in Liver Resection?
Guglielmi, A., Ruzzenente, A., Conci, S., Valdegamberi, A., & Iacono, C. (2012) · Digestive Surgery · doi:10.1159/000335713 · Cited by 373
Mao, S. A., Glorioso, J. M., & Nyberg, S. L. (2014) · Translational research · doi:10.1016/j.trsl.2014.01.005 · Cited by 260
Uriarte, I., Fernandez-Barrena, M. G., Monte, M., Latasa, M., Chang, H. C. Y., Carotti, S., Vespasiani-Gentilucci, U., Morini, S., Vicente, E., Concepcion, A., et al. (2013) · Gut · doi:10.1136/gutjnl-2012-302945 · Cited by 196
Metadata
- Authors
- Tucker, O. N., & Heaton, N.
- Affiliations
- King's College Hospital (GB)
- Corresponding author
- Heaton, N
- ORCID
- Heaton, N
- Venue
- Current Opinion in Critical Care
- Published
- 2005-04
- Volume
- 11
- Issue
- 2
- Pages
- 150-155
- ISSN
- 1070-5295 (ISSN-L)
- OpenAlex
- W1985757414
- Cited by
- 180
- References
- 65
- Citations by year
- 2025: 2 · 2024: 4 · 2023: 6 · 2022: 4 · 2021: 7 · 2020: 9 · 2019: 11 · 2018: 6 · 2017: 14 · 2016: 11 · 2015: 7 · 2014: 14 · 2013: 17 · 2012: 14
- FWCI
- 1.62
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Current Opinion in Critical Care (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Organ Transplantation Techniques and Outcomes
- Health Sciences › Medicine › Hepatology › Liver physiology and pathology
- Health Sciences › Medicine › Hepatology › Hepatocellular Carcinoma Treatment and Prognosis
- Keywords
- small-for-size syndrome, liver transplantation, extended hepatectomy, living donor liver transplantation, remnant liver volume, graft-to-recipient weight ratio, portal hypertension, preoperative embolization, split liver transplantation, marginal grafts, postoperative coagulopathy, liver regeneration
- MeSH terms
- Adult, Hepatectomy, Humans, Hypertension, Portal, Liver, Organ Size, Syndrome, Liver Transplantation, Hepatic Insufficiency
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
