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Cited by 455

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Marginal Structural Models as a Tool for Standardization

Sato, Tosiya, Matsuyama, Yutaka·2003·Epidemiology

Abstract

In this article, we show the general relation between standardization methods and marginal structural models. Standardization has been recognized as a method to control confounding and to estimate causal parameters of interest. Because standardization requires stratification by confounders, the sparse-data problem will occur when stratified by many confounders and one then might have an unstable estimator. A new class of causal models called marginal structural models has recently been proposed. In marginal structural models, the parameters are consistently estimated by the inverse-probability-of-treatment weighting method. Marginal structural models give a nonparametric standardization using the total group (exposed and unexposed) as the standard. In epidemiologic analysis, it is also important to know the change in the average risk of the exposed (or the unexposed) subgroup produced by exposure, which corresponds to the exposed (or the unexposed) group as the standard. We propose modifications of the weights in the marginal structural models, which give the nonparametric estimation of standardized parameters. With the proposed weights, we can use the marginal structural models as a useful tool for the nonparametric multivariate standardization.

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Metadata

Authors
Sato, T., & Matsuyama, Y.
Venue
Epidemiology
Published
2003-11
Volume
14
Issue
6
Pages
680-686
ISSN
1044-3983 (ISSN-L)
OpenAlex
W2110201971
Cited by
455
References
16
FWCI
1.63
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Marginal Structural Models as a Tool for Standardization. https://app.cochat.ai/papers/10.1097/01.ede.0000081989.82616.7d
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Sato, T., & Matsuyama, Y. (2003). Marginal Structural Models as a Tool for Standardization. Epidemiology. https://doi.org/10.1097/01.ede.0000081989.82616.7d

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.