The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Central nervous system outcomes in children with complex congenital heart disease
Abstract
PURPOSE OF REVIEW: To provide a brief overview of our current understanding of the types of neurodevelopmental sequelae in congenital heart disease survivors and to review the most recent studies from the past year, which have focused on 4 interrelated issues: (1) outcome studies, (2) the mechanism and etiology of central nervous system injury in children with CHD, (3) perioperative monitoring for brain injury, and (4) strategies for neuroprotection during cardiac surgery. RECENT FINDINGS: As the number of survivors of surgery for complex congenital heart disease continues to rise, it is recognized that there is an increased incidence of adverse neurological outcomes in the survivors. In particular, a pattern similar to that seen in premature infants is emerging, including learning disabilities, behavioral abnormalities, inattention and hyperactivity. Imaging studies have revealed a high prevalence of structural brain abnormalities and periventricular leukomalacia, fetal and postnatal cerebral blood flow is abnormal, postnatal oxygen delivery is decreased, and intraoperative support techniques and postoperative low cardiac output are associated with cerebral hypoperfusion. SUMMARY: The causes of these late developmental abnormalities are most likely sequential, cumulative and multifactorial.
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Newburger, J. W., Jonas, R. A., Wernovsky, G., Wypij, D., Hickey, P. R., Kuban, K., Farrell, D. M., Holmes, G. L., Helmers, S. L., Constantinou, J., et al. (1993) · New England Journal of Medicine · doi:10.1056/nejm199310073291501 · Cited by 702
Self-citationBellinger, D. C., Wypij, D., duPlessis, A. J., Rappaport, L. A., Jonas, R. A., Wernovsky, G., & Newburger, J. W. (2003) · The Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/s0022-5223(03)00711-6 · Cited by 681
Self-citationBellinger, D. C., Wypij, D., Kuban, K. C. K., Rappaport, L. A., Hickey, P. R., Wernovsky, G., Jonas, R. A., & Newburger, J. W. (1999) · Circulation · doi:10.1161/01.cir.100.5.526 · Cited by 579
Self-citationPreoperative cerebral blood flow is diminished in neonates with severe congenital heart defects
Licht, D. J., Wang, J., Silvestre, D. W., Nicolson, S. C., Montenegro, L. M., Wernovsky, G., Tabbutt, S., Durning, S. M., Shera, D. M., Gaynor, J. W., et al. (2004) · The Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2004.07.022 · Cited by 332
Self-citationLength of stay after infant heart surgery is related to cognitive outcome at age 8 years
Newburger, J. W., Wypij, D., Bellinger, D. C., du Plessis, A. J., Kuban, K. C. K., Rappaport, L. A., Almirall, D., Wessel, D. L., Jonas, R. A., & Wernovsky, G. (2003) · The Journal of Pediatrics · doi:10.1016/s0022-3476(03)00183-5 · Cited by 282
Self-citationEffect of prenatal diagnosis on outcomes in D-transposition of the great arteries
Bartlett, J. M., Wypij, D., Bellinger, D. C., Rappaport, L. A., Heffner, L. J., Jonas, R. A., & Newburger, J. W. (2004) · Pediatrics · doi:10.1542/peds.113.4.e335 · Cited by 101
Cited by
Brain maturation is delayed in infants with complex congenital heart defects
Licht, D. J., Shera, D. M., Clancy, R. R., Wernovsky, G., Montenegro, L. M., Nicolson, S. C., Zimmerman, R. A., Spray, T. L., Gaynor, J. W., & Vossough, A. (2009) · The Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2008.10.025 · Cited by 629
Self-citationBack, S. A. (2006) · Mental Retardation and Developmental Disabilities Research Reviews · doi:10.1002/mrdd.20107 · Cited by 326
Andropoulos, D. B., Hunter, J. V., Nelson, D. P., Stayer, S. A., Stark, A. R., McKenzie, E. D., Heinle, J. S., Graves, D. E., & Fraser, C. D. (2010) · The Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2009.08.022 · Cited by 318
Pathophysiology of glia in perinatal white matter injury
Back, S. A., & Rosenberg, P. A. (2014) · Glia · doi:10.1002/glia.22658 · Cited by 202
Is cardiac diagnosis a predictor of neurodevelopmental outcome after cardiac surgery in infancy?
Gaynor, J. W., Gerdes, M., Nord, A. S., Bernbaum, J., Zackai, E., Wernovsky, G., Clancy, R. R., Heagerty, P. J., Solot, C. B., McDonald-McGinn, D., et al. (2010) · The Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2010.07.069 · Cited by 88
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Metadata
- Authors
- Wernovsky, G., Shillingford, A. J., & Gaynor, J. W.
- Venue
- Current Opinion in Cardiology
- Published
- 2005-03
- Volume
- 20
- Issue
- 2
- Pages
- 94-99
- ISSN
- 0268-4705 (ISSN-L)
- OpenAlex
- W1996472330
- Cited by
- 159
- References
- 6
- FWCI
- 7.42
- Type
- journal article
- Language
- en
- Open access
- closed
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- Wernovsky, G., Shillingford, A. J., & Gaynor, J. W. (2005). Central nervous system outcomes in children with complex congenital heart disease. Current Opinion in Cardiology. https://doi.org/10.1097/01.hco.0000153451.68212.68
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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