Deconstructing an Adaptogen: Eleutherococcus senticosus
Abstract
The dried roots and rhizomes of Eleutherococcus senticosus (Araliacaea) plant are used in various preparations, primarily for its "adaptogenic" properties. An adaptogen supports health and prevents disease in both sick and healthy individuals through nonspecific effects, which neutralize various environmental and physical stressors while remaining relatively safe and free of side effects. The term "adaptogen," which has not been well defined scientifically, undermines the need for increased inquiry and research into the many promising effects of this herb. The primary clinical applications, pharmacology, evidence of efficacy, contraindications, drug interactions, and current clinical and scientific research are also reported.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Eleutherococcus senticosus is thought to exert its adaptogenic effects by influencing the hypothalamic-pituitary-adrenal axis.
“Eleutherococcus senticosus is thought to exert its adaptogenic effects by influencing the hypothalamic-pituitary-adrenal axis [44].”
From Plant Adaptogens—History and Future Perspectives (2021) · cites this paper as [44]
Cites
Eleutherococcus senticosus (Rupr. & Maxim.) Maxim. (Araliaceae) as an adaptogen: a closer look
Davydov, M., & Krikorian, A. D. (2000) · Journal of Ethnopharmacology · doi:10.1016/s0378-8741(00)00181-1 · Cited by 256 · see citing works
Drug Interactions Between Herbal and Prescription Medicines
Williamson, E. M. (2003) · Drug Safety · doi:10.2165/00002018-200326150-00002 · Cited by 166 · see citing works
Biological activities of Ginkgo extracts
Boonkaew, T., & Camper, N. D. (2005) · Phytomedicine · doi:10.1016/j.phymed.2003.06.008 · Cited by 50 · see citing works
Gaffney, B. T., Hügel, H., & Rich, P. (2001) · Medical Hypotheses · doi:10.1054/mehy.2000.1163 · Cited by 46 · see citing works
Cicero, A. F. G., Derosa, G., Brillante, R., et al. (2004) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2004.04.012 · Cited by 43 · see citing works
Assessment of the Effects of Eleutherococcus Senticosus on Endurance Performance
Goulet, E. D. B., & Dionne, I. J. (2005) · International Journal of Sport Nutrition and Exercise Metabolism · doi:10.1123/ijsnem.15.1.75 · Cited by 34 · see citing works
The effect of Kan Jang extract on the pharmacokinetics and pharmacodynamics of warfarin in rats
Hovhannisyan, A., Abrahamyan, H., Gabrielyan, E. S., et al. (2005) · Phytomedicine · doi:10.1016/j.phymed.2005.06.005 · Cited by 21 · see citing works
Monograph. Eleutherococcus senticosus.
(2006) · PubMed · Cited by 3 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Plant Adaptogens—History and Future Perspectives
Todorova, V., Ivanov, K., Delattre, C., Nalbantova, V., Karcheva-Bahchevanska, D., & Ivanova, S. (2021) · Nutrients · doi:10.3390/nu13082861 · Cited by 121 · see citing works
Todorova, V., Ivanov, K., & Ivanova, S. (2021) · Plants · doi:10.3390/plants11010064 · Cited by 56 · see citing works
- Authors
- Bleakney, T. L.
- Affiliations
- Drexel University (US)
- Corresponding author
- Bleakney, Tracy Lee
- Venue
- Holistic Nursing Practice
- Published
- 2008-07
- Volume
- 22
- Issue
- 4
- Pages
- 220-224
- ISSN
- 0887-9311 (ISSN-L)
- OpenAlex
- W2335022375
- Cited by
- 23
- References
- 8
- Citations by year
- 2025: 2 · 2023: 4 · 2022: 2 · 2021: 4 · 2019: 1 · 2017: 1 · 2016: 2 · 2014: 3 · 2013: 2 · 2012: 2
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Holistic Nursing Practice (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Medicinal Plants and Bioactive Compounds
- Health Sciences › Medicine › Complementary and alternative medicine › Phytochemicals and Medicinal Plants
- Health Sciences › Medicine › Complementary and alternative medicine › Herbal Medicine Research Studies
- Keywords
- Eleutherococcus senticosus, adaptogens, Siberian ginseng, herbal medicine, clinical efficacy, contraindications, drug interactions, stress response
- MeSH terms
- Fatigue, Humans, Phytotherapy, Plant Extracts, Plant Roots, Holistic Nursing, Eleutherococcus
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
