The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
WEIGHT LOSS: A NOVEL AND EFFECTIVE TREATMENT FOR URINARY INCONTINENCE
Abstract
PURPOSE: We evaluated the effect of weight loss on urinary incontinence (UI) in overweight and obese women. MATERIALS AND METHODS: A randomized, controlled clinical trial was conducted among overweight and obese women experiencing at least 4 UI episodes per week. Women were randomly assigned to a 3-month liquid diet weight reduction program (24 in the immediate intervention group) or a wait-list delayed intervention group (24 in the wait-list control group). Participants in the wait-list control group began the weight reduction program in month 3 of the study. All women were followed for 6 months after completing the weight reduction program. Wilcoxon tests were used to compare intergroup differences in change in weekly UI episodes and quality of life scores. RESULTS: A total of 48 women were randomized and 40 were assessed 3 months after randomization. Median (with 25% to 75% interquartile range [IQR]) baseline age was 52 years (IQR 47 to 59), weight was 97 kg (IQR 87 to 106) and UI episodes were 21 weekly (IQR 11 to 33). Women in the immediate intervention group had a 16 kg (IQR 9 to 20) weight reduction compared with 0 kg (IQR -2 to 2) in the wait-list control group (p <0.0001). The immediate intervention group experienced a 60% reduction (IQR 30% to 89%) in weekly UI episodes compared with 15% (IQR -9% to 25%) in the wait-list control group (p <0.0005) and had greater improvement in quality of life scores. Stress (p =0.003) and urge (p =0.03) incontinent episodes decreased in the immediate intervention vs wait-list control group. Following the weight reduction program the wait-list control group experienced a similar median reduction in weekly UI episodes (71%). Among all 40 women mean weekly UI episodes decreased 54% (95% CI 40% to 69%) after weight reduction and the improvement was maintained for 6 months. CONCLUSIONS: Weight reduction is an effective treatment for overweight and obese women with UI. Weight loss of 5% to 10% has an efficacy similar to that of other nonsurgical treatments and should be considered a first line therapy for incontinence.
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Cites
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
(2002) · New England Journal of Medicine · doi:10.1056/nejmoa012512 · Cited by 19,011
Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001
Mokdad, A. H., Ford, E. S., Bowman, B. A., Dietz, W. H., Vinicor, F., Bales, V. S., & Marks, J. S. (2003) · JAMA · doi:10.1001/jama.289.1.76 · Cited by 5,866
Cited by
Garvey, W. T., Mechanick, J. I., Brett, E. M., Garber, A. J., Hurley, D. L., Jastreboff, A. M., Nadolsky, K., Pessah-Pollack, R., & Plodkowski, R. (2016) · Endocrine Practice · doi:10.4158/ep161365.gl · Cited by 1,914
Lifestyle Intervention Is Associated With Lower Prevalence of Urinary Incontinence
Brown, J. S., Wing, R., Barrett-Connor, E., Nyberg, L. M., Kusek, J. W., Orchard, T. J., Ma, Y., Vittinghoff, E., Kanaya, A. M., & for the Diabetes Prevention Program Research Group (2006) · Diabetes Care · doi:10.2337/diacare.29.02.06.dc05-1781 · Cited by 154
Self-citationEffect of weight change on natural history of pelvic organ prolapse
Kudish, B. I., Iglesia, C. B., Sokol, R. J., Cochrane, B., Richter, H. E., Larson, J., Hendrix, S. L., & Howard, B. V. (2009) · Obstetrics & Gynecology · doi:10.1097/aog.0b013e318190a0dd · Cited by 140
Phelan, S., Kanaya, A. M., Subak, L. L., Hogan, P. E., Espeland, M. A., Wing, R. R., Burgio, K. L., DiLillo, V., Gorin, A. A., West, D. S., et al. (2012) · Journal of Urology · doi:10.1016/j.juro.2011.10.139 · Cited by 107
Self-citationThe role of obesity on urinary incontinence and anal incontinence in women: a review
Doumouchtsis, S., Loganathan, J., & Pergialiotis, V (2022) · BJOG: An International Journal of Obstetrics & Gynaecology · doi:10.1111/1471-0528.16848 · Cited by 79
Metadata
- Authors
- SUBAK, L. L., WHITCOMB, E., SHEN, H., SAXTON, J., VITTINGHOFF, E., & BROWN, J. S.
- Venue
- Journal of Urology
- Published
- 2005-07
- Volume
- 174
- Issue
- 1
- Pages
- 190-195
- ISSN
- 0022-5347 (ISSN-L)
- 1527-3792
- OpenAlex
- W2099954589
- Cited by
- 314
- References
- 2
- FWCI
- 9.95
- Type
- journal article
- Language
- en
- Open access
- closed
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